12 Results for "

R 406

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "R 406" in MCE Product Catalog:

40
R406
R406
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40 Publications Verification
Cat. No.: HY-12067
CAS No.: 841290-81-1
Purity:  96.70%
Target:  

Syk FLT3 Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

R406 is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 reduces immune complex-mediated inflammation . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
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40
R406 free base
R406 free base
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40 Publications Verification
Cat. No.: HY-11108
CAS No.: 841290-80-0
Purity:  99.80%
Target:  

Syk FLT3 Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

R406 free base is an orally available and competitive Syk/FLT3 inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. R406 free base reduces immune complex-mediated inflammation . R406 free base also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
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20
Fostamatinib
Fostamatinib
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20 Cited Publications
Cat. No.: HY-13038A
CAS No.: 901119-35-5
Purity:  99.70%
Synonyms: R788
Target:  

Syk FLT3

Research Areas:  

Inflammation/Immunology Cancer

Fostamatinib (R788) is the oral proagent of the active compound R406 . R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
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20
Fostamatinib Disodium
Fostamatinib Disodium
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20 Cited Publications
Cat. No.: HY-13038
CAS No.: 1025687-58-4
Purity:  99.88%
Synonyms: R788Disodium
Target:  

Syk FLT3

Research Areas:  

Inflammation/Immunology Cancer

Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406 . R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
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20
Fostamatinib disodium hexahydrate
Fostamatinib disodium hexahydrate
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20 Cited Publications
Cat. No.: HY-13038B
CAS No.: 914295-16-2
Purity:  99.51%
Synonyms: R788 disodium hexahydrate
Target:  

Syk FLT3

Research Areas:  

Inflammation/Immunology Cancer

Fostamatinib (R788) disodium hexahydrate is the oral proagent of the active compound R406 . R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM . R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM) .
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1
Annonacin
Annonacin
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1 Cited Publications
Cat. No.: HY-N2877
CAS No.: 111035-65-5
Category:  

Natural Products Neurological Disease Annonaceae Extract 500 - Internal Server Error | MedChemExpress

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