1 Result for "

RAPTA-C

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "RAPTA-C" in MCE Product Catalog:

Cat. No.: HY-130326
CAS No.: 372948-28-2
Purity:  99.30%
Synonyms: Ru(η6-p-cymene)Cl2(pta)
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

RAPTA-C is a ruthenium-based antimetastatic agent. RAPTA-C binds chromatin histones and interacts with DNA, leading to pH-dependent DNA damage and hypoxia selectivity. RAPTA-C inhibits angiogenesis, microvessel density, tumor growth, invasion, and proliferation, and induces apoptosis through the mitochondrial pathway, G2/M phase arrest, quiescence, and vascular normalization. RAPTA-C can be used in research on ovarian cancer, colorectal adenocarcinoma, breast cancer metastasis, and Ehrlich ascites carcinoma .
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