189 Results for "

RAW264

" in MedChemExpress (MCE) Product Catalog:
Products (189)

189 Results for "RAW264" in MCE Product Catalog:

165
165 Publications Verification
Cat. No.: HY-13982
CAS No.: 749886-87-1
Purity:  99.30%
Target:  

NF-κB

JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC50 of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation .
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8
8 Cited Publications
Cat. No.: HY-111152
CAS No.: 912798-42-6
Purity:  99.89%
Target:  

STAT

Research Areas:  

Cancer

ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC50 of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers .
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4
4 Cited Publications
Cat. No.: HY-N0617
CAS No.: 80651-76-9
Category:  

Cardiovascular Disease Moraceae Extract Plants Flavanonols Flavonoids Phenols Polyphenols Disease Research Fields Inflammation/Immunology 500 - Internal Server Error | MedChemExpress

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