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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
RBM39 modulator
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "RBM39 modulator" in MCE Product Catalog:
5
Target:
Research Areas:
E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a molecular glue that induces the targeted degradation of splicing factor RBM39 by recruiting the E3 ubiquitin ligase CUL4-RBX1-DDB1-DCAF15 (CRL4 DCAF15). E7820 is an angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 μg/ml. E7820 modulates α-1, α-2, α-3, and α-5 integrin mRNA expression. E7820 can be used for the study of acute myeloid leukemia (AML) .
Cat. No.: HY-190197
CAS No.: 3029716-79-5
Target:
Research Areas:
RBM39 modulator 1 is a molecular glue targeting RBM39. RBM39 modulator 1 modulates RBM39 protein activity and can be used in cancer research .
Cat. No.: HY-190198
CAS No.: 165668-69-9
Target:
Research Areas:
Cat. No.: HY-190199
CAS No.: 3029718-58-6
Target:
Research Areas:
RBM39 modulator 3 is a molecular glue targeting RBM39. RBM39 modulator 1 modulates RBM39 protein activity and can be used in cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
