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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
REP3123
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "REP3123" in MCE Product Catalog:
1
Target:
Research Areas:
CRS3123 (REP-3123) is an orally active antibacterial agent that targets methionyl-tRNA synthetase (MetRS). CRS3123 competitively displaces methionine from the active site of MetRS, preventing tRNA charging and protein synthesis, and exhibits greater selectivity for C. difficile MetRS than for human MetRS and Gram-negative bacterial MetRS. CRS3123 can be used in research on Clostridioides difficile infection and vancomycin-resistant enterococcal infection .
1
1 Cited Publications
Synonyms: REP-3123 dihydrochloride
Target:
Research Areas:
CRS3123 dihydrochloride (REP-3123 dihydrochloride) is an orally active antibacterial agent that targets methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride competitively displaces methionine from the active site of MetRS, preventing tRNA charging and protein synthesis, and exhibits greater selectivity for C. difficile MetRS than for human MetRS and Gram-negative bacterial MetRS. CRS3123 dihydrochloride can be used in research on Clostridioides difficile infection and vancomycin-resistant enterococcal infection .
Cat. No.: HY-115440R
CAS No.: 1013915-99-5
Synonyms: REP-3123 dihydrochloride (Standard)
Target:
Research Areas:
CRS3123 dihydrochloride (Standard) (REP-3123 dihydrochloride (Standard)) is the analytical standard of CRS3123 dihydrochloride (HY-115440). This product is intended for research and analytical applications. CRS3123 dihydrochloride (REP-3123 dihydrochloride) is an orally active antibacterial agent that targets methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride competitively displaces methionine from the active site of MetRS, preventing tRNA charging and protein synthesis, and exhibits greater selectivity for C. difficile MetRS than for human MetRS and Gram-negative bacterial MetRS. CRS3123 dihydrochloride can be used in research on Clostridioides difficile infection and vancomycin-resistant enterococcal infection .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
