288 Results for "

ROS accumulation

" in MedChemExpress (MCE) Product Catalog:
Products (288)

288 Results for "ROS accumulation" in MCE Product Catalog:

935
Erastin
Erastin
0 Images
935 Publications Verification
Cat. No.: HY-15763
CAS No.: 571203-78-6
Purity:  99.62%
Target:  

VDAC Ferroptosis Disulfidptosis

Research Areas:  

Cancer

Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity. Furthermore, Erastin can block the uptake of cystine mediated by SLC7A11 and also spares UMRC6-EV and -C91A cells from disulfidptosis under glucose starvation .
loading...
    loading...
View All Sizes
47
Dihydroartemisinin
Dihydroartemisinin
0 Images
47 Cited Publications
Cat. No.: HY-N0176
CAS No.: 71939-50-9
Synonyms: Dihydroqinghaosu; β-Dihydroartemisinin; Artenimol
Category:  

Infection Terpenoids Sesquiterpenes 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.