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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
RPL-554
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "RPL-554" in MCE Product Catalog:
1
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
Ensifentrine (RPL-554) is an inhaled dual inhibitor of PDE3 and PDE4 with IC50s of 0.4 nM and 1479 nM, respectively. Ensifentrine blocks PDE3 and PDE4 enzymes, thereby increasing the levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in lung cells, dilating the bronchi, and inhibiting the activation and migration of inflammatory cells. Ensifentrine can be used in the research of chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-111477
CAS No.: 298680-25-8
Synonyms: (E/Z)-RPL-554
Target:
Research Areas:
(E/Z)-Ensifentrine ((E/Z)-RPL-554) is the E/Z isomer of Ensifentrine (HY-119708). Ensifentrine is an inhaled dual PDE3 and PDE4 inhibitor. Ensifentrine can be used in research on chronic obstructive pulmonary disease (COPD) .
Cat. No.: HY-119708S
Synonyms: RPL-554-d6
Cat. No.: HY-119708A
CAS No.: 3098314-20-3
Synonyms: RPL-554 tosylate
Target:
Research Areas:
Ensifentrine (RPL-554) tosylate is an inhaled dual inhibitor of PDE3 and PDE4 with IC50s of 0.4 nM and 1479 nM, respectively. Ensifentrine tosylate blocks PDE3 and PDE4 enzymes, thereby increasing the levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) in lung cells, dilating the bronchi, and inhibiting the activation and migration of inflammatory cells. Ensifentrine tosylate can be used in the research of chronic obstructive pulmonary disease (COPD) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
