265 Results for "

S 4

" in MedChemExpress (MCE) Product Catalog:
Products (265)

265 Results for "S 4" in MCE Product Catalog:

6
Rat IgG2a kappa, Isotype Control
Rat IgG2a kappa, Isotype Control
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6 Publications Verification
Cat. No.: HY-P990679

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Rat IgG2a kappa, Isotype Control is a monoclonal antibody derived from rats, representing the immunoglobulin G2a (IgG2a) subclass with a kappa light chain. Rat IgG2a kappa, Isotype Control exhibits high efficiency in inducing K cell mediated cytotoxicity. Rat IgG2a kappa, Isotype Control is utilized in research investigating the roles of different immunoglobulin subclasses in tumor immunology. Rat IgG2a kappa, an isotype control, can be used as an isotype control for Anti-Mouse PD-1 Antibody (RMP1-14) (HY-P99144), Anti-Mouse CD11a/LFA-1α Antibody (M17/4) (HY-P990801), and Anti-Mouse IL-2 Antibody (S4B6-1) (HY-P990796) .
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4
GTx-007
GTx-007
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4 Cited Publications
Cat. No.: HY-12023
CAS No.: 401900-40-1
Purity:  99.61%
Synonyms: S-4
Target:  

Androgen Receptor

Research Areas:  

Cancer

GTx-007 (S-4) is an orally active and selective nonsteroidal androgen receptor (AR) modulator (SARM) and a partial agonist, with Ki of 4 nM. GTx-007 (S-4) is identified as SARMs with potent and tissue-selective in vivo pharmacological activity .
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L-Hydroxyproline
L-Hydroxyproline
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3 Cited Publications
Cat. No.: HY-40135
CAS No.: 51-35-4
Synonyms: (2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid
Category:  

Alkaloids Immune System Disorder Pyrrole Alkaloids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

L-Hydroxyproline, one of the hydroxyproline (Hyp) isomers, is a useful chiral building block in the production of many pharmaceuticals.
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3
SIRT4-IN-1
SIRT4-IN-1
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3 Cited Publications
Cat. No.: HY-163316
CAS No.: 3030697-87-8
Target:  

Sirtuin Glutamate Dehydrogenase (GLDH) PDHK

Research Areas:  

Metabolic Disease Cancer

SIRT4-IN-1 is a selective and potent Sirtuin 4 (Sirt4) inhibitor with an IC50 of 16 μM for hSirt4. SIRT4-IN-1 also inhibits hSirt1, hSirt2, hSirt3, hSirt4 and hSirt6. SIRT4-IN-1 competes with acyl peptide substrate for Sirt4's acyl binding site, and is noncompetitive with NAD +. SIRT4-IN-1 increases glutamate dehydrogenase (GDH) activity and rescues pyruvate dehydrogenase (PDH) activity. SIRT4-IN-1 inhibits adipocyte differentiation and suppresses Sirt4 overexpression-induced increased differentiation. SIRT4-IN-1 can be used for the researches of cancer and metabolic disease .
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L-Cycloserine
L-Cycloserine
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2 Cited Publications
Cat. No.: HY-B1122
CAS No.: 339-72-0
Synonyms: (S)-Cycloserine; (S)-4-Amino-3-isoxazolidone
Category:  

Microorganisms Neurological Disease Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics Cancer

Target:  

GABA Receptor HIV

L-Cycloserine ((S)-4-Amino-3-isoxazolidone) is an oral inhibitor of the enzyme gamma-aminobutyric acid (GABA) transaminase (GABA-t) and branched-chain transaminases in Mycobacterium tuberculosis. L-Cycloserine has anticonvulsant properties and inhibits the synthesis of neurotensin in mouse brains .
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2
CAIX Inhibitor S4
CAIX Inhibitor S4
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2 Cited Publications
Cat. No.: HY-110243
CAS No.: 1330061-67-0
Purity:  99.04%
Target:  

Carbonic Anhydrase

Research Areas:  

Cancer

CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII (CA IX/XII), with a Ki of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I (Ki=546 and 5600 nM, respectively). CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth .
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4,4'-Sulfonyldiphenol-d8
4,4'-Sulfonyldiphenol-d8
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1 Cited Publications
Cat. No.: HY-W011927S
CAS No.: 2483831-28-1
Synonyms: Bisphenol S (4,4'-Sulfonyldiphenol)-d8
4,4'-Sulfonyldiphenol-d8 (Bisphenol S (4,4'-Sulfonyldiphenol)-d8) is the deuterium labeled 4,4'-Sulfonyldiphenol (HY-W011927).4,4'-Sulfonyldiphenol (Bisphenol S; Bis(4-hydroxyphenyl) sulfone), a substitute for Bisphenol A (HY-18260), is widely used in industrial and consumer products. 4,4'-Sulfonyldiphenol is an estrogen receptor (ER) agonist and can competitively bind to thyroid hormone receptors (TR) with IC50 values for TRα and TRβ are 2650 μM and 2294 μM respectively, thereby affecting breast development and reducing the expression of androgen receptor (AR) in fetal testes. 4,4'-Sulfonyldiphenol promotes the progression of glioblastoma by upregulating the EZH2 mediated PI3K/AKT/mTOR pathway. Under chronic exposure, 4,4'-Sulfonyldiphenol can cause significant lipid deposition and dyslipidemia in the mouse liver by upregulating JunB and Atf3, and has a role in causing obesity at low doses. 4,4'-Sulfonyldiphenol induces intestinal inflammation by altering the intestinal microbiome. 4,4'-Sulfonyldiphenol accelerates the progression of atherosclerosis in zebrafish embryo larvae.
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Levoketoconazole
Levoketoconazole
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1 Cited Publications
Cat. No.: HY-B0105B
CAS No.: 142128-57-2
Synonyms: (-)-Ketoconazole; (-)-Ketoconazol; (-)-R 41400
Target:  

Cytochrome P450

Research Areas:  

Infection Inflammation/Immunology

Levoketoconazole ((-)-Ketoconazole) is the 2S,4R enantiomer derived from racemic Ketoconazole (HY-B0105). Levoketoconazole is a potent and orally active cortisol synthesis inhibitor. Levoketoconazole inhibits key steps in cortisol and testosterone synthesis by inhibiting CYP11B1, CYP11A1, and CYP17A1. Levoketoconazole can be used for research on endogenous Cushing’s syndrome .
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KH-4-43
KH-4-43
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1 Cited Publications
Cat. No.: HY-148602
CAS No.: 2813310-07-3
Purity:  99.99%
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

KH-4-43 is an inhibitor of E3 CRL4. KH-4-43 inhibits E3 CRL4's core ligase complex and exhibits anticancer activity. KH-4-43 has a binding Kd to E3 ROC1-CUL4A CTD or the highly related ROC1-CUL1 CTD at 83 nM or 9.4 μM, respectively .
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(2S,4R)-Hydroxy Itraconazole
(2S,4R)-Hydroxy Itraconazole
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Cat. No.: HY-12772
CAS No.: 112559-91-8
Purity:  99.80%
Synonyms: (2S,4R)-R-63373
Target:  

Fungal Drug Metabolite

Research Areas:  

Others

(2S,4R)-Hydroxy Itraconazole ((2S,4R)-R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
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(S)-4-(tert-Butoxy)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid
(S)-4-(tert-Butoxy)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid
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Cat. No.: HY-W007573
CAS No.: 34582-32-6
Target:  

Amino Acid Derivatives

Research Areas:  

Others

(S)-4-(tert-Butoxy)-3-((tert-butoxycarbonyl)amino)-4-oxobutanoic acid is an aspartic acid derivative .
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(4S)-4-Hydroxy-D-proline
(4S)-4-Hydroxy-D-proline
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Cat. No.: HY-34666
CAS No.: 3398-22-9
(4S)-4-Hydroxy-D-proline is a D-proline derivative and aglycon core for synthesis of cell wall O-glycans of the green alga Chlamydomonas reinhardtii .
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(S)-4-Benzyl-2-oxazolidone
(S)-4-Benzyl-2-oxazolidone
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Cat. No.: HY-41882
CAS No.: 90719-32-7
Synonyms: (-)-4-Benzyl-2-oxazolidinone
(S)-4-Benzyl-2-oxazolidinone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
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(3S,4S)-Tofacitinib
(3S,4S)-Tofacitinib
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Cat. No.: HY-40354C
CAS No.: 1092578-47-6
Target:  

JAK

Research Areas:  

Inflammation/Immunology

(3S,4S)-Tofacitinib is the less active S-enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
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(3S,4S)-A2-32-01
(3S,4S)-A2-32-01
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Cat. No.: HY-111532B
Purity:  98.15%
Target:  

ClpP Drug Isomer

Research Areas:  

Infection Cancer

(3S,4S)-A2-32-01 (compound 24 (S,S)) is the low/inactive (S,S)-enantiomer of A2-32-01. A2-32-01 is a potent caseinolytic protease (ClpP) inhibitor. (3S,4S)-A2-32-01 is applicable for oncology and microbiology research .
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Anti-Mouse IL-2 Antibody (S4B6-1)
Anti-Mouse IL-2 Antibody (S4B6-1)
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Cat. No.: HY-P990796

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

Anti-Mouse IL-2 Antibody (S4B6-1) is an anti-mouse IL-2 IgG2a monoclonal antibody. Anti-Mouse IL-2 Antibody (S4B6-1) can reduce CD4 + T cells and increase Tregs. Anti-Mouse IL-2 Antibody (S4B6-1) can induce Th17 cell differentiation. Anti-Mouse IL-2 Antibody (S4B6-1) can be used for research on cancer such as melanoma. The recommend isotype control of Anti-Mouse IL-2 Antibody (S4B6-1): Rat IgG2a kappa, Isotype Control (HY-P990679) .
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L-Altrose
L-Altrose
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Cat. No.: HY-W145488
CAS No.: 1949-88-8
Synonyms: (2R,3S,4S,5S)-2,3,4,5,6-Pentahydroxyhexanal
L-Altrose ((2R,3S,4S,5S)-2,3,4,5,6-Pentahydroxyhexanal) is an L-hexose carbohydrate that serves as an intermediate for research related to biochemical synthesis .
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S-(4-Hydroxybenzyl)glutathione
S-(4-Hydroxybenzyl)glutathione
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Cat. No.: HY-N8115
CAS No.: 129636-38-0
Category:  

Monophenols Orchidaceae Extract 500 - Internal Server Error | MedChemExpress

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