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6 Results for "

S180 sarcoma

" in MedChemExpress (MCE) Product Catalog:

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Obtustatin

4 Cited Publications

Cat. No.: HY-P1408

CAS No.: 404882-00-4

Target:

Integrin VEGFR

Research Areas:

Cancer

Obtustatin is a non-RGD disintegrin consisting of 41 residues. Obtustatin inhibits the adhesion of α1β1 integrin to type IV Collagen (HY-NP003), blocks α1β1 integrin signaling in endothelial cells, and suppresses FGF2-induced angiogenesis. Obtustatin inhibits tumor progression in mouse models and upregulates VEGF expression in sarcoma-bearing mice. Obtustatin can be used in research related to Lewis lung carcinoma and S-180 sarcoma .

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August 31

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Telomerase-IN-8

Cat. No.: HY-204056

CAS No.: 1884341-01-8

Target:

Telomerase

Research Areas:

Cancer

Telomerase-IN-8 is an orally active telomerase inhibitor, with an IC₅₀ value of 0.98 μM. Telomerase-IN-8 exhibits potent antiproliferative activity against multiple tumor cell lines, including PC3, Bcap-37, MGC-803 and HepG2. Telomerase-IN-8 demonstrates potent antitumor efficacy in S180 sarcoma or HepG2 hepatoma xenograft mice. Telomerase-IN-8 can be used for the study of telomerase-targeted anticancer .

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