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155 Results for "

SA

" in MedChemExpress (MCE) Product Catalog:

Products (155)

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ML-SA1

11 Cited Publications

Cat. No.: HY-108462

CAS No.: 332382-54-4

Purity: 99.44%

Target:

Dengue Virus TRP Channel Flavivirus

Research Areas:

Infection

ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC₅₀ value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral .

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Cutamesine dihydrochloride

7 Cited Publications

Cat. No.: HY-13510

CAS No.: 165377-44-6

Purity: 98.05%

Synonyms: SA4503 dihydrochloride; AGY94806 dihydrochloride

Target:

Sigma Receptor

Research Areas:

Neurological Disease

Cutamesine (SA4503) dihydrochloride is a potent and selective sigma 1 receptor agonist with an IC₅₀ of 17.4 nM in guinea pig brain membranes. Cutamesine dihydrochloride shows >100-fold less affinity for the sigma 2 receptor (IC₅₀ of 1784 nM). Cutamesine dihydrochloride has antidepressant effects .

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Cutamesine

7 Cited Publications

Cat. No.: HY-14813

CAS No.: 165377-43-5

Purity: 99.18%

Synonyms: SA4503; AGY 94806

Target:

Sigma Receptor

Research Areas:

Neurological Disease

Cutamesine (SA4503) is a potent and selective sigma 1 receptor agonist with an IC₅₀ of 17.4 nM in guinea pig brain membranes. Cutamesine shows >100-fold less affinity for the sigma 2 receptor (IC₅₀ of 1784 nM). Cutamesine has antidepressant effects .

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ML-SA5

4 Cited Publications

Cat. No.: HY-152182

CAS No.: 2418670-70-7

Purity: 99.57%

Target:

TRP Channel

Research Areas:

Cancer

ML-SA5 is a potent TRPML1 cation channel agonist that activates the entire endosomal TRPML1 (ML1) current in DMD myocytes with an EC₅₀ of 285 nM and is more potent than ML-SA1. ML-SA5 has anticancer activity and can inhibit tumour growth .

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