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10 Results for "

SHBG

" in MedChemExpress (MCE) Product Catalog:

Products (10)

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SHBG(141–161)

Cat. No.: HY-P10413

Target:

Androgen Receptor

Research Areas:

Metabolic Disease Endocrinology

SHBG 141-161 is a GPRC6A receptor agonist. SHBG 141-161 mimics the action of GPRC6A endogenous agonist uncarboxylated osteocalcin by binding to GPRC6A and promoting downstream signaling to increase testosterone and insulin secretion. SHBG 141-161 also reduces the affinity of GPRC6A to GDP protein by binding to the outer cell domain of GPRC6A thus affecting the dynamics of signal transduction. SHBG 141-161 can be used to study GPRC6A in energy metabolism and endocrine regulation .

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2-Iodoestradiol

Cat. No.: HY-118124

CAS No.: 24381-12-2

Target:

Endogenous Metabolite

Research Areas:

Others

2-Iodoestradiol is a potent human sex hormone binding globulin (SHBG) ligand with a remarkably high affinity for SHBG. 2-Iodoestradiol exhibits competition for the same binding site as dihydrotestosterone in binding to human SHBG. The binding affinity constant of 2-Iodoestradiol at physiological pH and 37 degrees Celsius is 2.4 x 10(9) M-1, exceeding that for SHBG. 2-Iodoestradiol has been shown to bind to serum albumin, but with lower affinity. The radioisotope 125I-derivative of 2-Iodoestradiol has been used to study the binding properties of human SHBG, demonstrating its potential application in biological research .

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SHBG Human Pre-designed siRNA Set A

Cat. No.: HY-RS12855

Target:

Small Interfering RNA (siRNA)

Research Areas:

Others

SHBG Human Pre-designed siRNA Set A contains three designed siRNAs for SHBG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Shbg Mouse Pre-designed siRNA Set A

Cat. No.: HY-RS19163

Target:

Small Interfering RNA (siRNA)

Research Areas:

Others

Shbg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Shbg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Equilenin

Cat. No.: HY-116865

CAS No.: 517-09-9

Purity: ≥95.0%

Target:

Endogenous Metabolite Aryl Hydrocarbon Receptor Cytochrome P450

Research Areas:

Metabolic Disease Cancer

Equilenin is a B-ring unsaturated estrogen discovered in pregnant mare urine and is one of the major components of Premarin, a drug commonly used for estrogen replacement therapy. Equilenin binds to estrogen receptors in the body and exerts effects similar to endogenous estrogens. Equilenin weakly binds to and activates the aryl hydrocarbon receptor (AhR) to induce CYP1A1 expression. Equilenin exhibits high affinity for sex hormone-binding globulin (SHBG/SBP) and is metabolized by CYP1A1/1B1 to 4-hydroxy and 17β-dihydro derivatives. Equilenin is used in breast cancer-related research .

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Shbg Rat Pre-designed siRNA Set A

Cat. No.: HY-RS25652

Target:

Small Interfering RNA (siRNA)

Research Areas:

Others

Shbg Rat Pre-designed siRNA Set A contains three designed siRNAs for Shbg gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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