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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
SHI-1
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "SHI-1" in MCE Product Catalog:
26
26 Publications Verification
Synonyms: RZ-2994
SHIN1 (RZ-2994) is a human serine hydroxymethyltransferse 1 and 2 (SHMT1/2) inhibitor with IC50s of 5 and 13 nM, respectively, in an in vitro assay.
4
4 Cited Publications
Synonyms: (+)-RZ-2994
(+)-SHIN1 ((+)-RZ-2994) is an active (+) enantiomer of SHIN1 .
2
2 Cited Publications
Synonyms: (-)-RZ-2994
Target:
Research Areas:
(-)-SHIN1 ((-)-RZ-2994) is an inactive (−) enantiomer of SHIN1 .
1
1 Cited Publications
Cat. No.: HY-P71141
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PTPN6; Protein-Tyrosine Phosphatase SHP-1; Protein Tyrosine Phosphatase Non-Receptor Type 6; Protein-Tyrosine Phosphatase 1C; PTP-1C; SH-PTP1; HCP; Tyrosine-Protein Phosphatase Non-Receptor Type; SHP-1; Hematopoietic Cell Phosphatase; HCPH; Protein-Tyrosi
Species:
Human
Source:
E. coli
1
Target:
Research Areas:
Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells .
Cat. No.: HY-113817
CAS No.: 1000010-33-2
Target:
Research Areas:
SHIP1 activator 1 is an SH3 domain-containing inositol 5-phosphatase regulator with SHIP1 activating activity. SHIP1 activator 1 retains its SHIA-1 activating ability by removing unnecessary functional groups. SHIP1 activator 1 is able to activate SHIP1 in vitro, inhibit Akt phosphorylation in MOLT-4 cells, and show dose-dependent activity in a mouse model of inflammation. SHIP1 activator 1 is an important chemical tool for evaluating the potential of SHIP1 activators as inhibitors of hematopoietic diseases involving abnormal PI3K cell signaling .
Cat. No.: HY-P83087
Synonyms: INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1
Cat. No.: HY-P83344
Synonyms: INPP5D; SHIP; SHIP1; Phosphatidylinositol 3; 4; 5-trisphosphate 5-phosphatase 1; Inositol polyphosphate-5-phosphatase of 145 kDa; SIP-145; SH2 domain-containing inositol 5'-phosphatase 1; SH2 domain-containing inositol phosphatase 1; SHIP-1
Cat. No.: HY-108440R
CAS No.: 326886-05-9
Target:
Research Areas:
Shz-1 (Standard) is the analytical standard of Shz-1 (HY-108440). This product is intended for research and analytical applications. Shz-1, a small cardiogenic molecule, induces various cardiac-specific genes including sarcomeric tropomyosin in P19CL6 cells. Shz-1 induces Nkx2.5 expression in mouse. Shz-1 activates the axolotl TPM4 promoter-driven ectopic expression in C2C12 cells .
Cat. No.: HY-189686
Research Areas:
SHC 1 is a dual HDAC8/HDAC6 inhibitor (HDAC8: IC50 = 0.036 μM; HDAC6: IC50 = 1.7 μM) that increases SMC3 acetylation levels. SHC 1 inhibits neuroblastoma cell proliferation, colony formation, and migration, induces caspase 3/7 activity, and exhibits antiproliferative activity against neuroblastoma cells superior to that against normal cells. SHC 1 can be used for research on neuroblastoma .
Cat. No.: HY-P73649
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: PTPN6; Protein-Tyrosine Phosphatase SHP-1; Protein Tyrosine Phosphatase Non-Receptor Type 6; Protein-Tyrosine Phosphatase 1C; PTP-1C; SH-PTP1; HCP; Tyrosine-Protein Phosphatase Non-Receptor Type; SHP-1; Hematopoietic Cell Phosphatase; HCPH; Protein-Tyrosi
Species:
Mouse
Source:
Sf9 insect cells
Cat. No.: HY-P705944
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SPI1; Hematopoietic Transcription Factor PU.1; Spi-1 Proto-Oncogene; 31 KDa Transforming Protein; SPI-A; Transcription Factor PU.1; SFPI1; Spleen Focus Forming Virus (SFFV) Proviral Integration Oncogene Spi1; SPI-1; Spleen Focus Forming Virus (SFFV) Provi
Species:
Human
Source:
E. coli
Cat. No.: HY-P81307AA
Synonyms: PTPN6; HCP; PTP1C; Tyrosine-protein phosphatase non-receptor type 6; Hematopoietic cell protein-tyrosine phosphatase; Protein-tyrosine phosphatase 1C; PTP-1C; Protein-tyrosine phosphatase SHP-1; SH-PTP1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
