1 Result for "

SHP2-IN-45

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "SHP2-IN-45" in MCE Product Catalog:

Cat. No.: HY-178983
CAS No.: 2949435-53-2
SHP2-IN-45 (Compound 6) is a potent, highly selective, and orally active SHP2 allosteric inhibitor. SHP2-IN-45 significantly reduces the expressions of IL-6, TNF-α, IL-1β, and iNOS. SHP2-IN-45 inhibits the polarization of M1-type macrophages. SHP2-IN-45 can inhibit the NF-κB pathway. SHP2-IN-45 can be used in the research of sepsis and acute lung injury .
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