83 Results for "

SK- cells

" in MedChemExpress (MCE) Product Catalog:
Products (83)

83 Results for "SK- cells" in MCE Product Catalog:

18
Phen Green SK diacetate (5/6-mixture)
Phen Green SK diacetate (5/6-mixture)
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18 Publications Verification
Cat. No.: HY-126823
CAS No.: 234075-45-7
Purity:  95.33%
Synonyms: PGSK diacetate (5/6-mixture)
Target:  

Fluorescent Dye

Research Areas:  

Others

Phen green SK (PGSK) diacetate (PGSK diacetate (5/6-mixture)) is a metal ion-sensitive fluorescent probe that can penetrate cell membranes. Phen green SK (PGSK) diacetate can react with a variety of metal ions, including Fe 2+, Cd 2+, Co 2+, Ni 2+, Zn 2+, etc. Phen green SK (PGSK) diacetate chelates Fe 2+, resulting in fluorescence quenching, which can be restored when a membrane-permeable chelator is added, thereby reflecting the changes in the intracellular chelatable iron pool. The excitation/emission maxima of Phen green SK diacetate are 507/532 nm, respectively .
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16
BQ-788
BQ-788
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16 Cited Publications
Cat. No.: HY-15894A
CAS No.: 173326-37-9
Purity:  98.66%
Target:  

Endothelin Receptor

Research Areas:  

Cardiovascular Disease Endocrinology Cancer

BQ-788 is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM .
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5
SK-575
SK-575
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5 Cited Publications
Cat. No.: HY-139156
CAS No.: 2523016-96-6
Purity:  99.86%
Target:  

PROTACs PARP

Research Areas:  

Cancer

SK-575 is a highly potent and specific proteolysis-targeting chimera (PROTAC) degrader of PARP1, with an IC50 of 2.30 nM. SK-575 potently inhibits the growth of cancer cells bearing BRCA1/2 mutations .
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2
UBA5-IN-1
UBA5-IN-1
0 Images
2 Cited Publications
Cat. No.: HY-148266
CAS No.: 1831169-11-9
Purity:  ≥98.0%
Target:  

E1/E2/E3 Enzyme

Research Areas:  

Cancer

UBA5-IN-1 (compound 8.5) is a selective UBA5 inhibitor with an IC50 value of 4.0 μM. UBA5-IN-1 inhibits cell proliferation of Sk-Luci6 cancer cells with high expression levels of UBA5 .
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1
ZK53
ZK53
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1 Cited Publications
Cat. No.: HY-149677
CAS No.: 3031789-26-8
Purity:  98.94%
Target:  

Mitochondrial Metabolism

Research Areas:  

Cancer

ZK53 is a selective activator of mitochondrial caseinolytic protease P (HsClpP) (EC50: 1.37?μM for α-casein hydrolysis by HsClpP). ZK53 is is inactive toward bacterial ClpP proteins. ZK53 induces apoptosis in H1703, H520 and SK-MES-1 cells. ZK53 induces dysregulation of mitochondrial functions in lung squamous cell carcinoma (LUSC) cells. ZK53 inhibits tumor growth in H1703 xenograft mouse model .
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Acesulfame potassium
Acesulfame potassium
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Cat. No.: HY-D0195
CAS No.: 55589-62-3
Target:  

mTOR Autophagy ERK PD-1/PD-L1

Research Areas:  

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Acesulfame potassium is a synthetic sweetener. Long-term use of Acesulfame potassium can affect cognitive function, possibly by altering the neurometabolic functions in mice. Acesulfame potassium can suppress autophagic degradation of PD-L1 in RIL-175 and SK-Hep1 cells through the ERK1/2-mTORC1-ULK1 pathway, which may be related to immune evasion in cancer cells. Acesulfame potassium can be used in research on neurological diseases, metabolic disorders, cancer, and immune evasion .
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Taccalonolide A
Taccalonolide A
0 Images
Cat. No.: HY-N2416
CAS No.: 108885-68-3
Category:  

Taccaceae Extract Plants Disease Research Fields 500 - Internal Server Error | MedChemExpress

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