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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
SKI606
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "SKI606" in MCE Product Catalog:
26
Research Areas:
Bosutinib is an orally active Src/Abl tyrosine kinase inhibitor with IC50 of 1.2 nM and 1 nM, respectively .
26
Cat. No.: HY-10158AR
CAS No.: 918639-08-4
Synonyms: SKI-606 hydrate (Standard)
Target:
Research Areas:
Bosutinib (Standard) (SKI-606 (Standard)) hydrate is the analytical standard of Bosutinib hydrate (HY-10158A). This product is intended for research and analytical applications. Bosutinib hydrate is an oraly activel Src/Abl tyrosine kinase inhibito with IC50s of 1.2 nM and 1 nM, respectively.
Cat. No.: HY-10158S1
Synonyms: SKI-606-13C,d3
Cat. No.: HY-107449
CAS No.: 380843-81-2
Synonyms: N-Desmethyl-SKI-606
N-Desmethyl-Bosutinib (N-Desmethyl-SKI-606) is the N-demethylated metabolite of Bosutinib (HY-10158), and also acts as a Src kinase inhibitor with an IC50 of 1.1 nM. N-Desmethyl-Bosutinib inhibits the enzymatic activity of Src kinase as well as Src-dependent cell proliferation, and can be used in the research of chronic myeloid leukemia .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
