41 Results for "

SNAIL

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "SNAIL" in MCE Product Catalog:

2
ZY-444
ZY-444
0 Images
2 Cited Publications
Cat. No.: HY-142870
CAS No.: 1802650-31-2
Purity:  98.70%
Target:  

Pyruvate Carboxylase (PC) Apoptosis β-catenin ERK Wnt

Research Areas:  

Cancer

ZY-444 is an anti-cancer agent, targeting pyruvate carboxylase (PC). ZY-444 suppresses the Wnt/β-catenin/Snail signaling pathway by blocking nuclear translocation of β-catenin. ZY-444 selectively inhibits proliferation, migration, and invasion and induces apoptosis in cancer cells. ZY-444 exhibits potent anti-tumor in cancer mouse models. ZY-444 can be used for the study of breast cancer, lung cancer (NSCLC), prostate cancer and iodine-refractory thyroid cancer .
loading...
    loading...
View All Sizes
1
Snailase, Snail gastrointestinal
Snailase, Snail gastrointestinal
0 Images
1 Cited Publications
Cat. No.: HY-E70130
CAS No.: 158736-45-9
Target:  

Others

Research Areas:  

Others

Snailase, Snail gastrointestinal is an enzyme mixture composed of more than 20 enzymes, which is often used for enzymatic hydrolysis of purified flavonoid glycosides. Snailase can be obtained from the digestive tract and includes cellulase, sucrase, hemicellulase, pectinase, polygalacturonase, protease, etc .
loading...
    loading...
View All Sizes
1
Telocinobufagin
Telocinobufagin
0 Images
1 Cited Publications
Cat. No.: HY-N0885
CAS No.: 472-26-4
Synonyms: Telobufotoxin; Telocinobufogenin
Category:  

Animals Other Diseases Disease Research Fields Steroids

Target:  

JAK STAT mTOR PI3K Akt Polo-like Kinase (PLK) Na+/K+ ATPase Apoptosis Bacterial

Telocinobufagin (Telobufotoxin; Telocinobufogenin) is an orally active bufadienolide with potential anti-tumor effects. Telocinobufagin exerts its anti-cancer effects on non-small cell carcinoma, osteosarcoma, thyroid cancer, breast cancer and head and neck squamous cell carcinoma by inhibiting the STAT3, JAK2/STAT3, LARP1-mTOR, PI3K/Akt/Snail and PLK1 pathways, and can also induce tumor cell apoptosis. Telocinobufagin enhances the Th1 immune response and protects against Salmonella typhimurium infection. Telocinobufagin has a strong cardiac-stimulating effect by inhibiting the activity of Na +/K +-ATPase, and it can promote renal fibrosis. Telocinobufagin demonstrates non-opioid analgesic effects in various acute pain models .
loading...
    loading...
View All Sizes
1
SNAI1 Antibody
SNAI1 Antibody
0 Images
1 Cited Publications
Cat. No.: HY-P81135
Synonyms: SNAI1_HUMAN; Zinc finger protein SNAI1; SNAI1; SNAH; SNAI 1; SNA; SNAIL1; dJ710H13.1; Protein SNAIL homolog 1 (Protein sna); Protein SNAIL homolog 1; Protein sna;

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Monkey

loading...
    loading...
View All Sizes
Ammonium sulphate,≥99.0%,AR
Ammonium sulphate,≥99.0%,AR
0 Images
Cat. No.: HY-Y0261A
CAS No.: 7783-20-2
Target:  

Environmental Pollutants Biochemical Assay Reagents

Research Areas:  

Others

Ammonium sulphate,≥99.0%,AR is an inorganic sulfate salt used for molecular biology . Ammonium sulphate,≥99.0%,AR can be used to precipitate proteins, separate antibodies, and enhance antigen-antibody reactions. Ammonium sulphate,≥99.0%,AR can serve as a nitrogen source in plant fertilizers and has developmentally toxicity to freshwater snails, but increases the number of Anopheles africanus and Culex mosquito larvae in rice paddies. Ammonium sulphate,≥99.0%,AR also inhibits the conversion of glucose to ascorbic acid in plants .
loading...
    loading...
View All Sizes
CYD19
CYD19
0 Images
Cat. No.: HY-144315
CAS No.: 2415281-52-4
Purity:  99.76%
Synonyms: SNAIL/HDAC-IN-1
Target:  

HDAC

Research Areas:  

Cancer

CYD19 is a potent Snail/HDAC dual target inhibitor. CYD19 displays potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM and potent inhibition against Snail with a Kd of 0.18 μM. CYD19 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis .
loading...
    loading...
View All Sizes
Amprolium hydrochloride
Amprolium hydrochloride
0 Images
Cat. No.: HY-B0937A
CAS No.: 137-88-2
Target:  

Parasite Cholinesterase (ChE)

Research Areas:  

Infection

Amprolium hydrochloride is a thiamine transporter inhibitor and antiparasitic agent with oral activity and blood-brain barrier penetration. Amprolium hydrochloride blocks thiamine transport at the blood-brain barrier and intestine, and competitively inhibits thiamine pyrophosphokinase, inducing thiamine pyrophosphate deficiency and impairing carbohydrate synthesis. Amprolium hydrochloride induces oxidative stress, alters antioxidant enzyme activity, and inhibits acetylcholinesterase (AchE) activity. Amprolium hydrochloride disrupts reproductive organs and gametogenesis, and causes histopathological and ultrastructural damage to multiple organs. Amprolium hydrochloride induces thiamine deficiency, reduces body weight gain in mice, and causes psychomotor behavioral changes and nephropathy. Amprolium hydrochloride exhibits molluscicidal activity against the terrestrial snail Eobania vermiculata, and reduces the shedding of Eimeria meleagrimitis oocysts in feces and litter. Amprolium hydrochloride can be used for research on thiamine deficiency and coccidiosis .
loading...
    loading...
View All Sizes
GN25
GN25
0 Images
Cat. No.: HY-117280
CAS No.: 1227401-27-5
Purity:  98.81%
Target:  

MDM-2/p53

Research Areas:  

Cancer

GN25 is a specific p53-Snail binding inhibitor with antitumor effects .
loading...
    loading...
View All Sizes
Ferric phosphate
Ferric phosphate
0 Images
Cat. No.: HY-B1647
CAS No.: 10045-86-0
Ferric phosphate is used as food and feed supplement, particularly in bread enrichment. Ferric phosphate is also used as a fertilizer and as a molluscicide for a variety of slugs and snails including Deroceras reticulatum, D.laeve, Arion subfuscus .
loading...
    loading...
View All Sizes
CYY292
CYY292
0 Images
Cat. No.: HY-162153
CAS No.: 2644673-04-9
Target:  

FGFR

Research Areas:  

Cancer

CYY292 is an FGFR1 inhibitor that specifically targets the FGFR1/AKT/Snail pathway in GBM cells. CYY292 dose-dependently inhibits cancer cell proliferation, epithelial-mesenchymal transition, stemness, invasion, and migration in vitro .
loading...
    loading...
View All Sizes
PELI1-IN-1
PELI1-IN-1
0 Images
Cat. No.: HY-157435
CAS No.: 3034889-94-3
Purity:  98.14%
Target:  

E1/E2/E3 Enzyme Cytochrome P450 Proteasome

Research Areas:  

Cancer

PELI1-IN-1 (compound 3d) is a potent inhibitor of PELI1, E3 ubiquitin ligase. PELI1-IN-1 has anti-tumPELI1-IN-1, a Resveratrol (HY-16561) derivative, is an orally active PELI1 Inhibitor (Kd = 8.2 μM). PELI1-IN-1 markedly interrupts the interaction of PELI1 and SNAIL/SLUG, and inhibits the K63-polyubiquitization of SNAIL/SLUG by PELI1, subsequently downregulating the protein levels of epithelial-mesenchymal transition (EMT) effectors SNAIL/SLUG. PELI1-IN-1 significantly reduces the level of SNAIL, SLUG and Vimentin without affecting the PELI1 expression. PELI1-IN-1 targets the FHA domain of PELI1 and disrupts the interaction, leading to the anti-metastasis of TNBC cells in vitro and in vivo. PELI1-IN-1 shows no evident toxicity in vivo .
loading...
    loading...
View All Sizes
Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa
Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa
0 Images
Cat. No.: HY-P1904
CAS No.: 98495-35-3
Category:  

Natural Products Animals

Target:  

Others

Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa is a FMRF-like peptide from visceral and somatic muscles of the snail Helix aspersa. FMRF (Phe-Met-Arg-Phe) is a neuropeptide peptide consisting of 4 amino acid residues .
loading...
    loading...
View All Sizes
SNAI1 Human Pre-designed siRNA Set A
SNAI1 Human Pre-designed siRNA Set A
Cat. No.: HY-RS13470
Target:  

Small Interfering RNA (siRNA)

Research Areas:  

Others

SNAI1 Human Pre-designed siRNA Set A contains three designed siRNAs for SNAI1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

loading...
    loading...
View All Sizes
Lys-Conopressin-G
Lys-Conopressin-G
0 Images
Cat. No.: HY-P5166
CAS No.: 111317-91-0
Target:  

Inhibitory Antibodies

Research Areas:  

Others

Lys-Conopressin-G, a vasotocin-like peptide, can be isolated from the venom of the worm-hunting snail (conus imperialis) .
loading...
    loading...
View All Sizes
Amprolium
Amprolium
0 Images
Cat. No.: HY-B0937
CAS No.: 121-25-5
Target:  

Parasite Cholinesterase (ChE)

Research Areas:  

Infection

Amprolium is a thiamine transporter inhibitor and antiparasitic agent with oral activity and blood-brain barrier penetration. Amprolium blocks thiamine transport at the blood-brain barrier and intestine, and competitively inhibits thiamine pyrophosphokinase, inducing thiamine pyrophosphate deficiency and impairing carbohydrate synthesis. Amprolium induces oxidative stress, alters antioxidant enzyme activity, and inhibits acetylcholinesterase (AchE) activity. Amprolium disrupts reproductive organs and gametogenesis, and causes histopathological and ultrastructural damage to multiple organs. Amprolium induces thiamine deficiency, reduces body weight gain in mice, and causes psychomotor behavioral changes and nephropathy. Amprolium exhibits molluscicidal activity against the terrestrial snail Eobania vermiculata, and reduces the shedding of Eimeria meleagrimitis oocysts in feces and litter. Amprolium can be used for research on thiamine deficiency and coccidiosis .
loading...
    loading...
View All Sizes
AO-022
AO-022
0 Images
Cat. No.: HY-159130
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

AO-022 is a potent TALDO1 allosteric inhibitor. AO-022 decreases the expression of vimentin and snail. AO-022 shows antiproliferative activity and antitumor activity. AO-022 has the potential for the research of breast cancer .
loading...
    loading...
View All Sizes
Conantokin-T
Conantokin-T
0 Images
Cat. No.: HY-P1287
CAS No.: 127476-26-0
Target:  

iGluR

Research Areas:  

Neurological Disease

Conantokin-T is a γ-carboxyglutamate-containing, N-methyl-D-aspartate (NMDA) antagonist peptidewith an IC50 value of 2 μM. Conantokin-T inhibits NMDA receptor-mediated calcium influx in central nervous system neurons. Conantokin-T can be purified from the venom of the fish-hunting cone snail, Conus tulipa .
loading...
    loading...
View All Sizes
Inophyllum B
Inophyllum B
0 Images
Cat. No.: HY-142074
CAS No.: 41135-06-2
Synonyms: (+)-Inophyllum B
Category:  

Rosaceae Extract Coumarins Phenylpropanoids Plants 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.