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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
SR-BI
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "SR-BI" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: Block lipid transport-1
Target:
Research Areas:
BLT-1, a thiosemicarbazone copper chelator, is a selective scavenger receptor B, type 1 (SR-BI) inhibitor. BLT-1 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. BLT-1 is a potent HCV entry inhibitor .
3
3 Cited Publications
Cat. No.: HY-19900
CAS No.: 1252679-52-9
Research Areas:
ITX5061 is an orally active type II non-competitive p38 MAPK inhibitor. ITX5061 increases HDL-C levels by inhibiting SR-BI activity. ITX5061 also moderately elevates ApoA-I levels. ITX5061 reduces early atherosclerotic lesions in the aortic arch of mice fed an atherogenic diet. ITX5061 can be used in the research of atherosclerosis .
Cat. No.: HY-139007
CAS No.: 251917-79-0
Target:
Research Areas:
BLT-4 is a specific, reversible inhibitor of scavenger receptor, class B, type I (SR-BI). BLT-4 inhibits the transfer of lipids between high-density lipoproteins (HDL) and cells mediated by SR-BI. .
Cat. No.: HY-124666
CAS No.: 1604821-55-7
Research Areas:
ML279 is a potent scavenger receptor, class B, type I (SR-BI) inhibitor. ML279 can inhibit SR-BI-mediated lipid uptake by stabilizing the binding of HDL to SR-BI (EC50 = 0.27 μM). ML279 can be used for the researches of infection and cardiovascular disease, such as atherosclerosis and HCV infection .
Cat. No.: HY-19616
CAS No.: 1604821-43-3
Research Areas:
ML278 is a scavenger receptor-BI (SR-BI) inhibitor with an IC50 of 0.93 nM in mice. ML278 inhibits SR-BI-mediated lipid uptake, enhances the binding of high-density lipoprotein (HDL) to SR-BI, blocks the uptake of oleoylcholesteryl ester from HDL, and reversibly inhibits the efflux of free cholesterol to HDL particles. ML278 can be used in studies related to atherosclerotic coronary artery disease .
Cat. No.: HY-154857
CAS No.: 89947-80-8
Research Areas:
1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine is a glycerophosphorylcholine, consisting of glycerol phosphate, choline and palmitic acid. It accumulates in vivo at sites of oxidative stress. 1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine may be a ligand of scavenger receptors class B, while oxidized phospholipids oxPC(CD36) are potent ligands of scavenger receptors class B (CD36 and SR-BI). Oxidized phospholipids (oxPLs) also play an important role in tumor apoptosis, may be elevated in malignant biliary strictures .
Synonyms: SDZ-HDL 376
Research Areas:
HDL376 is a scavenger receptor class B type I (SR-BI) inhibitor. HDL376 directly inhibits SR-BI-mediated lipid transport in cells and in liposomes reconstituted with purified SR-BI (IC50 = 0.22 μM). HDL376 can be used for the research of atherosclerotic coronary artery disease .
Cat. No.: HY-P81415A
Synonyms: CLA1; SRB1; CLA-1; SR-BI; CD36L1; HDLQTL6; Scavenging Receptor SR-BI
Cat. No.: HY-120433
CAS No.: 109940-24-1
Research Areas:
BLT-3 is an inhibitor of scavenger receptor class B type I (SR-BI) that exerts reversible, non-cell-type-specific inhibitory effects on SR-BI-mediated lipid transport. BLT-3 inhibits SR-BI-mediated selective lipid uptake from HDL as well as cholesterol efflux from cells to HDL. BLT-3 enhances the binding of HDL to SR-BI. BLT-3 is applicable to research related to atherosclerosis and coronary heart disease .
Cat. No.: HY-RS18098
Target:
Research Areas:
Scarb1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scarb1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS12488
Target:
Research Areas:
SCARB1 Human Pre-designed siRNA Set A contains three designed siRNAs for SCARB1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P76086
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SCARB1; CD36 And LIMPII Analogous 1; Prev. CD36L1; Scavenger Receptor Class B, Member 1; SR-BI; Scavenger Receptor Class B Type III; CLA-1; CD36 Antigen-Like 1; SRB1; CD36 Antigen; CLA1; HDLQTL6; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Rece
Species:
Mouse
Source:
HEK293
Cat. No.: HY-P76658
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SCARB1; CD36 And LIMPII Analogous 1; Prev. CD36L1; Scavenger Receptor Class B, Member 1; SR-BI; Scavenger Receptor Class B Type III; CLA-1; CD36 Antigen-Like 1; SRB1; CD36 Antigen; CLA1; HDLQTL6; CD36 Antigen (Collagen Type I Receptor, Thrombospondin Rece
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
