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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
8 Results for "
SRSF1
" in MedChemExpress (MCE) Product Catalog:
Products (8)
8 Results for "SRSF1" in MCE Product Catalog:
13
13 Cited Publications
Cat. No.: HY-117661
CAS No.: 1818389-84-2
Research Areas:
SPHINX31 is a potent and selective SRPK1 inhibitor, with an IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). SPHINX31 also decreases the mRNA expression of pro-angiogenic VEGF-A165a isoform. SPHINX31 can be used to research neovascular eye disease [1] .
Cat. No.: HY-170935
SRSF1-IN-1 is a SRSF1 inhibitor. SRSF1-IN-1 inhibits SRSF1 expression, thereby modulating the splicing of Bcl-x pre-mRNA. SRSF1-IN-1 inhibits the proliferation of various cancer cells. SRSF1-IN-1 induces apoptosis in gastric cancer cells, reduces Bcl-xl expression, and upregulates cleaved PARP and caspase 3. SRSF1-IN-1 induces autophagy and promotes cell death. SRSF1-IN-1 exhibits anti-tumor activity in a mouse gastric cancer xenograft model. SRSF1-IN-1 can be used for the research of various cancers including liver cancer, gastric cancer, breast cancer, colon cancer, glioma, and melanoma [1].
Cat. No.: HY-RS13790
Target:
Research Areas:
SRSF1 Human Pre-designed siRNA Set A contains three designed siRNAs for SRSF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23624
Target:
Research Areas:
Srsf1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Srsf1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17174
Target:
Research Areas:
Srsf1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Srsf1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-125201
CAS No.: 2252153-37-8
Target:
Research Areas:
Indazole 1 is a potent CDC2-like kinase 2 (CLK2) inhibitor (IC50=12.3 nM). Indazole 1 inhibits the phosphorylation of SR proteins (e.g., SRSF1, SRSF3) and modulates alternative splicing of Wnt signaling-related genes. Indazole 1 is promising for research of osteoarthritis [1].
Cat. No.: HY-P700524
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SRSF1; SR Splicing Factor 1; Prev. SFRS1; MGC5228; Serine/Arginine-Rich Splicing Factor 1; Splicing Factor, Arginine/Serine-Rich 1 (Splicing Factor 2, Alternate Splicing Factor), Isoform CRA_f; ASF; Serine And Arginine Rich Splicing Factor 1 Transcript Va
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
