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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
SSR180711
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "SSR180711" in MCE Product Catalog:
Cat. No.: HY-167824
CAS No.: 298198-52-4
Target:
Research Areas:
SSR180711 is an orally active, blood-brain barrier-penetrant α7-nAChR partial agonist (EC50 = 0.9-4.4 µM; Ki = 22/14 nM for binding to rat/human α7-nAChR; IC50 = 30/18 nM). SSR180711 reverses NMDA receptor antagonist-induced cognitive and latent inhibition deficits by enhancing glutamatergic and GABAergic neurotransmission, acetylcholine and Dopamine (HY-B0451) release, and long-term potentiation. SSR18071 is used in research on schizophrenia and Alzheimer's disease .
Cat. No.: HY-19411
CAS No.: 446031-79-4
Target:
Research Areas:
SSR180711 hydrochloride is an orally active, selective and reversible α7 acetylcholine nicotinic receptor (n-AChRs) partial agonist. SSR180711 hydrochloride can act on rat α7 n-AChR (Ki=22 nM; IC50=30 nM) and human α7 n-AChR (Ki=14 nM; IC50=18 nM). SSR180711 hydrochloride increases glutamatergic neurotransmission, ACh release and long-term potentiation (LTP) in the hippocampus .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
