42 Results for "

ST2

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "ST2" in MCE Product Catalog:

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3
3 Cited Publications
Cat. No.: HY-P99444
CAS No.: 2173054-79-8
Synonyms: MSTT 1041A; RG 6149
Astegolimab (MSTT 1041A; RG 6149) is a human IgG2 monoclonal antibody. Astegolimab blocks IL-33 signaling by targeting the IL-33 receptor ST2. Astegolimab reduces p53 expression, mitigates IL33-upregulated SASP factors such as IL1α, IL6 and MCP1. Astegolimab mitigates IL33-increased p-p65/p65 ratio. Astegolimab blocks CM-induced neutrophil extracellular trap (NET) formation. Astegolimab is used in chronic obstructive pulmonary disease (COPD) and myocardial research [2] .
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1
1 Cited Publications
Cat. No.: HY-P70615
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL1; ST2V; Interleukin 1 Receptor Like 1; Homolog Of Mouse Growth STimulation-Expressed; DER4; Suppressor Of Tumorigenicity 2; ST2; Interleukin 1 Receptor-Like 1 Isoform 2; T1; Interleukin 1 Receptor-Like 1 Isoform 1; Interleukin-1 Receptor-Like 1; Int
Species:  
Human
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P76666
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SULT2B1; Sulfotransferase 2B1; Sulfotransferase Family 2B Member 1; ST2B1; HSST2; Sulfotransferase Family Cytosolic 2B Member 1; Sulfotransferase Family, Cytosolic, 2B, Member 1; HydroxySTeroid Sulfotransferase SULT2B1a; HydroxySTeroid Sulfotransferase 2
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-168532
CAS No.: 3099811-61-4
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

ST2-IN-1 is a ST2 inhibitor. ST2-IN-1 blocks the binding interaction between ST2 and IL-33, thereby attenuating the downstream ST2/IL-33 signaling pathway. ST2-IN-1 reduces IL-1β release from mast cells and alleviates ST2 upregulation in cells. ST2-IN-1 can be used for research on inflammatory and immune-related diseases .
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Cat. No.: HY-P99729
CAS No.: 2222865-46-3
Synonyms: GSK 3772847; CNTO-7160

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Melrilimab (GSK 3772847; CNTO-7160) is a humanized IgG2σ monoclonal antibody that targets the IL-33 receptor ST2 and blocks the IL-33/ST2 signaling pathway by binding to the ST2 protein. Melrilimab is applicable to research related to asthma and atopic dermatitis [2].
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Cat. No.: HY-155193
Purity:  99.77%
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

XY-52 (Compound 32) is a Stimulation-2 (ST2) inhibitor, with an IC50 value of 5.68 μM in AlphaLISA assay, and 4.59 μM in HEK-Blue assay. XY-52 increases proinflammatory T-cell proliferation. XY-52 reduces the plasma sST2 and IFNγ biomarkers in the graft versus host disease (GVHD) mice model .
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Cat. No.: HY-P991633

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

TQC2938 is a humanized IgG2 monoclonal antibody inhibitor targeting Stimulation-2 (ST2). TQC2938 inhibits the ST2/IL-33 signaling pathway, reduces the level of downstream Th2 cytokines (such as IL-4, IL-5, and IL-13) and eosinophils as well as other inflammatory cells. TQC2938 can be used for inflammatory diseases like asthma research .
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Cat. No.: HY-RS06725
Research Areas:  

Others

IL1RL1 Human Pre-designed siRNA Set A contains three designed siRNAs for IL1RL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS29497
Research Areas:  

Metabolic Disease

GAL3ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for GAL3ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Components
GAL3ST2 siRNA-1: 5 nmol (HPLC)
GAL3ST2 siRNA-2: 5 nmol (HPLC)
GAL3ST2 siRNA-3: 5 nmol (HPLC)
siRNA Negative Control: 5 nmol (HPLC)
FAM-labeled siRNA Negative Control: 5 nmol (HPLC)
GAPDH siRNA Positive Control: 5 nmol (HPLC)
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Cat. No.: HY-W060417
CAS No.: 1019158-02-1
Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology Cancer

iST2-1 is an Stimulation-2 (ST2) inhibitor with an IC50 value of 46.65 μM, blocks interaction between ST2 and IL-33, inhibits downstream signaling. iST2-1 functions as an immunomodulator, reduces proliferation of CD4 + and CD8 + T cells, increases regulatory T cell populations, reduces IFN-γ +CD4 + T cell populations, increases Foxp3 +CD4 + regulatory T cell populations in the gastrointestinal tract. iST2-1 reduces plasma soluble ST2 and IFN-γ levels, reduces graft-versus-host disease scores, improves survival in graft-versus-host disease animal models, preserves graft-versus-tumor effect. iST2-1 can be used for the research of graft-versus-host disease [2].
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Cat. No.: HY-174607
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.
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Cat. No.: HY-P11298
CAS No.: 2120397-85-3
d-T101 peptide, a human hormone-peptide, is a T1/ST2 receptor ligand. d-T101 peptide binds to the T1/ST2 receptor and activates caspases 8, 9 and 3 mediated apoptosis, together with activation of JNKinase and p38 MAPKinase. d-T101 peptide also changes Golgi structural with function loss and downregulation of the endoplasmic reticulum (ER) stress repair mechanism. d-T101 peptide has immunostimulatory and anticancer activity, selectively induces apoptosis in proliferating cancer cells and increases IL-2 and IFN-γ expression as well as the recruitment of NK cells and M1 macrophages to the tumor site [2] .
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Cat. No.: HY-RS06378
Research Areas:  

Others

HS3ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for HS3ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS06383
Research Areas:  

Others

HS6ST2 Human Pre-designed siRNA Set A contains three designed siRNAs for HS6ST2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P811303
Synonyms: DER4; ST2; T1; Interleukin-1 receptor-like 1; Protein ST2

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P82116
Synonyms: HST; ST2; STD; hSTa; DHEAS; ST2A1; ST2A3; DHEA-ST

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P705134
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL1RL1; ST2V; Interleukin 1 Receptor Like 1; Homolog Of Mouse Growth STimulation-Expressed; DER4; Suppressor Of Tumorigenicity 2; ST2; Interleukin 1 Receptor-Like 1 Isoform 2; T1; Interleukin 1 Receptor-Like 1 Isoform 1; Interleukin-1 Receptor-Like 1; Interleukin 1 Receptor-Related Protein; FIT-1; Growth STimulation-Expressed; IL33R; Protein ST2; ST2L
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-RS12584
Research Areas:  

Others

SDCBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for SDCBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P992440

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

PF-06817024 is a high affinity, humanized antibody that binds IL-33. PF-06817024 binds to IL-33, prevents IL-33 from binding to receptor ST2, and inhibits downstream type 2 inflammatory responses. PF-06817024 can be used for the research of allergic diseases [2].
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Cat. No.: HY-P71343
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SULT2A1; ST2; Prev. STD; DehydroepiandroSTerone Sulfotransferase; DHEA-ST; Bile-Salt Sulfotranasferase 2A1; Sulfotransferase Family, Cytosolic, 2A, DehydroepiandroSTerone (DHEA)-Preferring, Member 1; HydroxySTeroid Sulfotransferase; Sulfotransferase 2A1;
Species:  
Human
Source:  
E. coli
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