1 Result for "

ST539

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ST539" in MCE Product Catalog:

Cat. No.: HY-114383
CAS No.: 1040754-67-3
ST-539 is an orally active USP30 inhibitor that crosses the blood-brain barrier, with an IC50 of 0.37 μM. ST-539 blocks USP30-mediated removal of ubiquitin from Parkin substrates, induces Parkin-mediated mitophagy and apoptosis during mitochondrial stress, and inhibits the AKT/mTOR signaling pathway. ST-539 can be used for research on T-cell leukemia, Parkinson's disease, and colon adenocarcinoma .
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