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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
SUMO1
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "SUMO1" in MCE Product Catalog:
39
39 Publications Verification
Target:
Research Areas:
ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50 values of 3 and 11 nM, respectively) compared with NAE/NEDD8 and UAE/ubiquitin (IC50> values of 32 μM and >100 μM, respectively) [1].
2
2 Cited Publications
Cat. No.: HY-P80351
Synonyms: DAP1 antibody;
GAP modifying protein 1 antibody;
GMP 1 antibody;
OFC10 antibody;
PIC 1 antibody;
PIC1 antibody;
SENP2 antibody;
Sentrin 1 antibody;
Sentrin antibody;
Small ubiquitin related modifier 1 antibody;
Small ubiquitin-like modifier 1 antibody;
Small ubiquitin-related modifier 1 antibody;
SMT3 antibody;
SMT3 homolog 3 antibody;
SMT3 suppressor of mif two 3 homolog 1 antibody;
SMT3, yeast, homolog 3 antibody;
Smt3C antibody;
SMT3H3 antibody;
SUMO-1 antibody;
SUMO1 antibody;
SUMO1_HUMAN antibody;
Ubiquitin homology domain protein PIC1 antibody;
Ubiquitin Like 1 antibody;
Ubiquitin like protein SMT3C antibody;
Ubiquitin like protein UBL1 antibody;
Ubiquitin-homology domain protein PIC1 antibody;
Ubiquitin-like protein SMT3C antibody;
Ubiquitin-like protein UBL1 antibody;
UBL 1 antibody;
UBL1 antibody
1
1 Cited Publications
Cat. No.: HY-P71288
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SENP2; Sentrin (SUMO1) Specific Peptidase 2; SUMO Specific Peptidase 2; Sentrin/SUMO-Specific Protease SENP2; KIAA1331; SMT3-Specific Isopeptidase 2; SMT3IP2; Sentrin-Specific Protease 2; AXAM2; DKFZp762A2316; SUMO1/Sentrin/SMT3 Specific Peptidase 2; Smt3
Species:
Human
Source:
E. coli
Target:
Research Areas:
HB007 is a SUMO1 molecular glue degrader targeting CAPRIN1 and FBXO42. HB007 selectively binds CAPRIN1 to induce CAPRIN1-FBXO42 interaction, recruits SUMO1 to the CAPRIN1-CUL1-FBXO42 E3 ligase complex, and drives SUMO1 ubiquitination and degradation without affecting SUMO2/3. HB007 induces TCF4 deSUMOylation and proteasomal degradation to inhibit StarD7 transcriptional activity, reduces StarD7 mRNA and protein levels, and triggers ER stress and ROS production. HB007 can be used for the research of brain cancer, breast cancer, colon cancer, lung cancer [1] .
Cat. No.: HY-RS14025
Target:
Research Areas:
SUMO1 Human Pre-designed siRNA Set A contains three designed siRNAs for SUMO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17276
Target:
Research Areas:
Sumo1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sumo1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-190188
CAS No.: 195066-24-1
Target:
Research Areas:
SUMO1 Degrader-1 is a blood-brain barrier-penetrant and selective SUMO1 degrader with antitumor activity. SUMO1 Degrader-1 induces ubiquitination and proteasomal degradation of SUMO1 and blocks the binding of SUMO1 to substrate proteins. SUMO1 Degrader-1 improves survival in mice with intracranial brain tumor xenografts and inhibits the progression of donor-derived xenograft tumors from human colon cancer, breast cancer, and non-small cell lung cancer. HB007 (HY-139662), a derivative of SUMO1 Degrader-1, is a molecular glue degrader. SUMO1 Degrader-1 can be used in cancer-related research, such as glioblastoma, breast cancer, etc [1].
Cat. No.: HY-RS23730
Target:
Research Areas:
Sumo1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Sumo1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P86396
Synonyms: SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43; Small ubiquitin-related modifier 1; SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein
Cat. No.: HY-P70997
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SUMO1; SMT3 Homolog 3; Prev. UBL1; SMT3 Suppressor Of Mif Two 3 Homolog 1 (Yeast), Isoform CRA_b; SMT3H3; SMT3 Suppressor Of Mif Two 3 Homolog 1 (S. Cerevisiae); SMT3C; SMT3 Suppressor Of Mif Two 3 Homolog 1 (Yeast); GMP1; SMT3 Suppressor Of Mif Two 3 Hom
Species:
Human
Source:
E. coli
Cat. No.: HY-P71643
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SAE1; SUMO-1 Activating Enzyme Subunit 1, Isoform CRA_a; SUMO1 Activating Enzyme Subunit 1; Ubiquitin-Like Protein SUMO-1 Activating Enzyme; AOS1; SUMO-1 Activating Enzyme E1 N Subunit; Sua1; Sentrin/SUMO-Activating Protein AOS1; Ubiquitin-Like 1-Activati
Species:
Human
Source:
E. coli
Cat. No.: HY-108702R
CAS No.: 1644342-14-2
Target:
Research Areas:
ML-792 (Standard) is the analytical standard of ML-792 (HY-108702). This product is intended for research and analytical applications. ML-792 is a potent and selective inhibitor of SAE/SUMO1 and SAE/SUMO2 in enzymatic assays (IC50 values of 3 and 11 nM, respectively) compared with NAE/NEDD8 and UAE/ubiquitin (IC50> values of 32 μM and >100 μM, respectively) [1].
Cat. No.: HY-P80905
Synonyms: SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43; Small ubiquitin-related modifier 1; SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein
Cat. No.: HY-P80905A
Synonyms: SUMO1; SMT3C; SMT3H3; UBL1; OK/SW-cl.43; Small ubiquitin-related modifier 1; SUMO-1; GAP-modifying protein 1; GMP1; SMT3 homolog 3; Sentrin; Ubiquitin-homology domain protein PIC1; Ubiquitin-like protein SMT3C; Smt3C; Ubiquitin-like protein
Cat. No.: HY-P705707
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SUMO1; SMT3 Homolog 3; Prev. UBL1; SMT3 Suppressor Of Mif Two 3 Homolog 1 (Yeast), Isoform CRA_b; SMT3H3; SMT3 Suppressor Of Mif Two 3 Homolog 1 (S. Cerevisiae); SMT3C; SMT3 Suppressor Of Mif Two 3 Homolog 1 (Yeast); GMP1; SMT3 Suppressor Of Mif Two 3 Hom
Species:
Others
Source:
P. pastoris
Cat. No.: HY-P71289
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SENP7; SUMO1/Sentrin Specific Peptidase 7; SUMO Specific Peptidase 7; SUMO1/Sentrin Specific Protease 7; Sentrin/SUMO-Specific Protease SENP7; KIAA1707; Sentrin-Specific Protease 7; SUSP2; SUMO-1-Specific Protease 2; SSP2
Species:
Human
Source:
E. coli
Cat. No.: HY-P705923
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SENP5; SUMO1/Sentrin Specific Protease 5; SUMO Specific Peptidase 5; Sentrin-Specific Protease 5; Sentrin/SUMO-Specific Protease SENP5; MGC27076; SUMO1/Sentrin Specific Peptidase 5; SUMO1/Sentrin Specific Peptidase 5, Isoform CRA_a
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P701473
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SENP6; SUMO1/Sentrin Specific Protease 6; SUMO Specific Peptidase 6; Sentrin-Specific Protease 6; SUSP1; SUMO-1-Specific Protease 1; KIAA0797; SSP1; Sentrin/SUMO-Specific Protease SENP6; Alternative Protein SENP6; SUMO1/Sentrin Specific Peptidase 6; 28100
Species:
Human
Source:
E. coli
Cat. No.: HY-P701472
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: SENP6; SUMO1/Sentrin Specific Protease 6; SUMO Specific Peptidase 6; Sentrin-Specific Protease 6; SUSP1; SUMO-1-Specific Protease 1; KIAA0797; SSP1; Sentrin/SUMO-Specific Protease SENP6; Alternative Protein SENP6; SUMO1/Sentrin Specific Peptidase 6; 28100
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P702804
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SENP6; SUMO1/Sentrin Specific Protease 6; SUMO Specific Peptidase 6; Sentrin-Specific Protease 6; SUSP1; SUMO-1-Specific Protease 1; KIAA0797; SSP1; Sentrin/SUMO-Specific Protease SENP6; Alternative Protein SENP6; SUMO1/Sentrin Specific Peptidase 6; 28100
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
