2 Results for "

Saos-2 cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Saos-2 cells" in MCE Product Catalog:

Cat. No.: HY-116926
CAS No.: 27259-98-9
Deoxynybomycin is an antibiotic, that can be isolated from Streptomyces, and antibacterial activity against Staphylococcus aureus. Deoxynybomycin is the inhibitor for DNA gyrase and Topoisomerase I. Deoxynybomycin induces expression of p21/WAF1, exhibits cytotoxicity and induces apoptosis in cancer cells Saos-2, TMK-1, and THP-1 .
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Cat. No.: HY-174240
Target:  

Drug Derivative

Research Areas:  

Cancer

Anticancer agent 274 (Compound 1) is a Sorafenib (HY-10201) analog. Anticancer agent 274 can inhibit the growth of tumor cells, with IC50 values of 0.034 μM and 0.042 μM against SaOS-2 and MNNG-HOS cells, respectively. Anticancer agent 274 has relatively low toxicity to normal cells and can be used in the research of tumors such as osteosarcoma .
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