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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
108 Results for "
Serpin
" in MedChemExpress (MCE) Product Catalog:
Products (108)
108 Results for "Serpin" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-P7054
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinF1; Testis Tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived Factor; Serpin F
Species:
Human
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P70975
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA5; Acrosomal Serine Protease Inhibitor; Prev. PLANH3; PAI-3; Prev. PCI; Plasminogen Activator Inhibitor III; PROCI; Plasminogen Activator Inhibitor-3; PAI3; Plasminogen Activator Inhibitor 3; Protein C Inhibitor; Serpin A5; Serine (Or Cysteine) Pro
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P71077
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinE1; Endothelial Plasminogen Activator Inhibitor; Prev. PLANH1; Serpin E1; Prev. PAI1; PAI-1; PAI; Serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade E (Nexi
Species:
Human
Source:
HEK293
2
2 Cited Publications
Cat. No.: HY-P7419
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA12; Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Serpin Family A Member 12; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 12; Vaspin; Serpin A12; OL-64; Vis
Species:
Human
Source:
E. coli
1
Target:
Research Areas:
Serpin B9-IN-1 (BTCA) is an inhibitor that specifically targets Serpin B9 (SB9); SB9 is a natural inhibitor of granzyme B (GrB) , but may promote the metastasis of lung cancer cells into the bone marrow. SB9-overexpressing cancer cells promote proliferation and metastasis in an immune cell-dependent manner by binding to GrB. Inhibition of SB9 by Serpin B9-IN-1 significantly inhibits immunotherapy of lung cancer bone metastases in the caudal artery (CA) mouse model (LCBM) .
1
1 Cited Publications
Cat. No.: HY-P77198
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: SerpinB4; Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 4; Prev. SCCA2; Serpin B4; Squamous Cell Carcinoma Antigen 2; Protease Inhibitor (Leucine-Serpin); SCCA-2; Squamous Cell Carcinoma Antigen 1; PI11; SCCA2/SCCA1 Fusion Protein; LEUPIN; Leupi
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P73372
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinF1; Testis Tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived Factor; Serpin F
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73412
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA3; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3, Isoform CRA_a; Prev. AACT; Growth-Inhibiting Protein 24; ACT; Growth-Inhibiting Protein 25; Alpha-1-Antichymotrypsin; Alpha-1 Antichymotrypsin; Serpin Peptidase
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70498A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinF1; Testis Tissue Sperm-Binding Protein Li 70n; Prev. PEDF; Serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1; EPC-1; Proliferation-Inducing Protein 35; Pigment Epithelium-Derived Factor; Serpin F
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71143
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinA4; Testicular Secretory Protein Li 22; Prev. PI4; Peptidase Inhibitor 4; KST; Kallikrein Inhibitor; Kallistatin; Serpin A4; KLST; PI-4; KAL; Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4, Isoform CRA_a; Serine (Or Cysteine) Proteinase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4; Protease Inhibitor 4 (Kallistatin); Serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4; Serpin Family A Member 4; SSerpin Family A Member 4
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71133
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinE1; Endothelial Plasminogen Activator Inhibitor; Prev. PLANH1; Serpin E1; Prev. PAI1; PAI-1; PAI; Serpin Peptidase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1; Serine (Or Cysteine) Proteinase Inhibitor, Clade E (Nexin, Plasminogen Activator Inhibitor Type 1), Member 1; Plasminogen Activator Inhibitor, Type I; Serpin Family E Member 1; Plasminogen Activator Inhibitor 1
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72831
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SerpinC1; Signal Peptide Antithrombin Part 1; Prev. AT3; Antithrombin III; ATIII; SerpinC1 Protein; Antithrombin-III; Antithrombin; Serine (Or Cysteine) Proteinase Inhibitor, Clade C (Antithrombin), Member 1; ATIII-R2; Serpin Peptidase Inhibitor, Clade C
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71303
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinB1; Epididymis Secretory Protein Li 27; Prev. ELANH2; Peptidase Inhibitor 2; MNEI; HEL-S-27; PI2; M/NEI; LEI; PI-2; EI; Serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 1, Isoform CRA_a; Leukocyte Elastase Inhibitor; Protease Inhibitor 2 (Ant
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P73526
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SerpinG1; Serine (Or Cysteine) Proteinase Inhibitor, Clade G (C1 Inhibitor), Member 1, (Angioedema, Hereditary); Prev. C1NH; Serine/Cysteine Proteinase Inhibitor Clade G Member 1 Splice Variant 2; Plasma Protease C1 Inhibitor; Serine/Cysteine Proteinase I
Species:
Human
Source:
HEK293
Cat. No.: HY-E70194
CAS No.: 137010-42-5
Synonyms: V8 protease; Glu-C
Target:
Research Areas:
Endoproteinase Glu-C (MS grade) is a serine proteinase. Endoproteinase GluC is able to hydrolyze some serpins and all classes of mammalian immunoglobulins .
Cat. No.: HY-P991422
Synonyms: DS9231; TS-23; CSL-301
Target:
Research Areas:
Target:
Research Areas:
ARN1468 (compound 5) is an orally active and potent SerpinA3n inhibitor. ARN1468 can inhibit serpins activity would set the protease free to further reduce prion accumulation. ARN1468 shows anti-prion effect in ScGT1 RML, ScGT1 22L, ScN2a RML, and ScN2a 22L cell lines, with EC50 values of 8.64, 19.3, 11.2, and 6.27 μM .
Cat. No.: HY-P991629
Target:
Research Areas:
Cat. No.: HY-174484
OVA mRNA (5moU) encodes the ovalbumin (OVA) protein, a member of the serpin superfamily and the predominant glycoprotein found in egg whites. It is a commonly used antigen for immunization and biochemical studies and is an established model allergen for airway hyper-responsiveness.
Cat. No.: HY-P11413
CAS No.: 139446-70-1
Research Areas:
Cardiovascular Disease Metabolic Disease Inflammation/Immunology
PAI-1 is a serine protease inhibitor (SERPIN). PAI-1 binds to and irreversibly inhibits uPA, tPA and furin; it also interacts with vitronectin, α1-acid glycoprotein, CRT, TLR4, proteasome α-3 subunit, uPAR, LRP1, Integrin αvβ3 and thrombin. PAI-1 regulates fibrinolysis, extracellular matrix turnover, cell migration, angiogenesis, inflammatory response and tissue remodeling; it mediates epithelial-mesenchymal transition (EMT)/endothelial-mesenchymal transition (EndMT), apoptosis and thrombus stabilization. PAI-1 can be used in research related to sepsis, acute lung injury, cardiovascular diseases, tissue fibrosis, diabetic nephropathy, obstructive nephropathy and non-insulin-dependent diabetes mellitus .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
