7 Results for "

Spider toxin

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Spider toxin" in MCE Product Catalog:

9
9 Cited Publications
Cat. No.: HY-12506A
CAS No.: 1049731-36-3
Purity:  98.50%
Synonyms: 1-Naphthylacetyl spermine trihydrochloride
Target:  

iGluR

Research Areas:  

Neurological Disease

Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
loading...
    loading...
9
9 Cited Publications
Cat. No.: HY-12506
CAS No.: 122306-11-0
Purity:  96.30%
Synonyms: 1-Naphthylacetyl spermine
Target:  

iGluR

Research Areas:  

Neurological Disease

Naspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist.
loading...
    loading...
Cat. No.: HY-P5786
Synonyms: HpTx1
Research Areas:  

Neurological Disease

Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8 .
loading...
    loading...
Cat. No.: HY-P5162
Target:  

Sodium Channel

Research Areas:  

Inflammation/Immunology

Dc1a potently promotes opening of the German cockroach Nav channel (BgNav1). Dc1a is a toxin can be isolated from the desert bush spider Diguetia canities .
loading...
    loading...
Cat. No.: HY-P2699
CAS No.: 152617-90-8
Synonyms: GrTx; ω-GsTx SIA
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

ω-Grammotoxin SIA (GrTx) is P/Q and N-type voltage-gated Calcium channels inhibitor. ω-Grammotoxin SIA is also a protein toxin that can be obtained from spider venom. ω-Grammotoxin SIA has the potential to study neurological diseases as well as cardiovascular diseases .
loading...
    loading...
Cat. No.: HY-P5813
Synonyms: β-TRTX-cd1a; β-Theraphotoxin-cd1a
Target:  

Calcium Channel

Research Areas:  

Neurological Disease

Cd1a is a β-toxin derived from the African spider Ceratogyrus darlingi. Cd1a can regulate calcium ion channels. Cd1a inhibits human calcium ion channels (Cav2.2)(IC502.6 μM) and mouse sodium ion channels (Nav1.7). Cd1a can be used in the development of peripheral pain treatment drugs .
loading...
    loading...
Cat. No.: HY-P5164
Target:  

Sodium Channel

Research Areas:  

Neurological Disease

GrTx1 is a peptide toxin originally isolated from the venom of the spider Grammostola rosea. GrTx1 blocks sodium channel, with IC50s of 0.63 μM, 0.23 μM, 0.77 μM, 1.29 μM, 0.63 μM and 0.37 μM for Nav1.1, Nav1.2, Nav1.3, Nav1.4, Nav1.6 and Nav1.7, repectively . GrTx1 can be used for neurological disease research .
loading...
    loading...