74 Results for "

Squalene

" in MedChemExpress (MCE) Product Catalog:
Products (74)

74 Results for "Squalene" in MCE Product Catalog:

3
Squalene
Squalene
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3 Cited Publications
Cat. No.: HY-N1214
CAS No.: 111-02-4
Synonyms: Super Squalene; trans-Squalene; AddaVax
Category:  

Cardiovascular Disease Triterpenes Plants Other Families Extract Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms Animals Terpenoids Disease Research Fields

Target:  

Endogenous Metabolite Reactive Oxygen Species (ROS) Fungal

Squalene (Super Squalene) is an intermediate product in the synthesis of cholesterol, and shows several pharmacological properties such as hypolipidemic, hepatoprotective, antiatherosclerotic, cardioprotective, antioxidant, and antitumour activity .
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29
FIN56
FIN56
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29 Publications Verification
Cat. No.: HY-103087
CAS No.: 1083162-61-1
Purity:  98.03%
Target:  

Ferroptosis

Research Areas:  

Others

FIN56 is a specific inducer of ferroptosis. FIN56 induces ferroptosis by inducing degradation of GPX4. FIN56 also binds to and activates squalene synthase .
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19
Terbinafine
Terbinafine
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19 Cited Publications
Cat. No.: HY-17395A
CAS No.: 91161-71-6
Synonyms: TDT 067
Target:  

Fungal Bacterial Antibiotic

Research Areas:  

Infection

Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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19
Terbinafine hydrochloride
Terbinafine hydrochloride
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19 Cited Publications
Cat. No.: HY-17395
CAS No.: 78628-80-5
Synonyms: TDT 067 hydrochloride
Target:  

Fungal Bacterial Antibiotic

Research Areas:  

Infection

Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria . Terbinafine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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16
NB-598
NB-598
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16 Cited Publications
Cat. No.: HY-16343
CAS No.: 131060-14-5
Target:  

COX

Research Areas:  

Metabolic Disease

NB-598 is a potent and competitive inhibitor of squalene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway. NB-598 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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16
NB-598 Maleate
NB-598 Maleate
0 Images
16 Cited Publications
Cat. No.: HY-16343C
CAS No.: 155294-62-5
Target:  

COX

Research Areas:  

Metabolic Disease

NB-598 Maleate is a potent and competitive inhibitor of squalene epoxidase (SE), and suppresses triglyceride biosynthesis through the farnesol pathway. NB-598 (Maleate) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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6
YM-53601
YM-53601
0 Images
6 Cited Publications
Cat. No.: HY-100313A
CAS No.: 182959-33-7
Purity:  98.23%
Target:  

Farnesyl Transferase HCV

Research Areas:  

Infection Metabolic Disease

YM-53601, a squalene synthase inhibitor, reduces plasma cholesterol and triglyceride levels in vivo . YM-53601 inhibits squalene synthase derived from human hepatoma cells with an IC50 of 79 nM. Lipid-lowering agent . YM-53601 is also an inhibitor of farnesyl-diphosphate farnesyltransferase 1 (FDFT1) enzyme activity and abrogates HCV propagation .
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2
FR194738
FR194738
0 Images
2 Cited Publications
Cat. No.: HY-100303A
CAS No.: 204067-52-7
Purity:  98.76%
Target:  

Squalene Monooxygenase

Research Areas:  

Metabolic Disease

FR194738 is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
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2
FR194738 free base
FR194738 free base
0 Images
2 Cited Publications
Cat. No.: HY-100303
CAS No.: 204067-45-8
Purity:  99.84%
Target:  

Squalene Monooxygenase

Research Areas:  

Metabolic Disease

FR194738 free base is a squalene epoxidase inhibitor. FR194738 inhibits squalene epoxidase activity in HepG2 cell homogenates with an IC50 of 9.8 nM.
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1
Lapaquistat acetate
Lapaquistat acetate
0 Images
1 Cited Publications
Cat. No.: HY-16274
CAS No.: 189060-13-7
Synonyms: TAK-475
Target:  

Farnesyl Transferase

Research Areas:  

Metabolic Disease

Lapaquistat acetate (TAK-475) is a squalene synthase inhibitor, blocking the conversion of farnesyl diphosphate (FPP) to squalene in the cholesterol biosynthesis pathway . Lapaquistat acetate is effective at lowering low-density lipoprotein cholesterol, but it might cause liver damage. Lapaquistat acetate is used for hypercholesterolemia and mevalonate kinase deficiency (MKD) research .
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1
Butenafine Hydrochloride
Butenafine Hydrochloride
0 Images
1 Cited Publications
Cat. No.: HY-17396
CAS No.: 101827-46-7
Synonyms: KP363 Hydrochloride
Target:  

Fungal Antibiotic

Research Areas:  

Infection

Butenafine Hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, works by inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
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1
Diallyl disulfide
Diallyl disulfide
0 Images
1 Cited Publications
Cat. No.: HY-W015635
CAS No.: 2179-57-9
Category:  

Natural Products Plants Liliaceae Extract Disease Research Fields 500 - Internal Server Error | MedChemExpress

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