76 Results for "

T cell receptor complex

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "T cell receptor complex" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-102022
CAS No.: 158021-47-7
Purity:  95.59%
Synonyms: α-GalCer; KRN7000
α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) .
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3
3 Cited Publications
Cat. No.: HY-P10102
CAS No.: 629628-53-1
Research Areas:  

Inflammation/Immunology Cancer

Kp7-6 is a Fas mimetic peptide and also a Fas/FasL antagonist. Kp7-6 specifically binds to Fas and FasL, disrupts receptor complexes, and blocks downstream apoptosis signaling pathways. Kp7-6 inhibits the phosphorylation of ERK1-2, induces the phosphorylation of IκBα, and activates NF-κB. Kp7-6 inhibits the activation of caspase-8, caspase-3 and JNK, and suppresses human amylin-induced β-cell apoptosis. Kp7-6 inhibits FasL-induced lymphoid cytotoxicity and apoptosis. Kp7-6 reduces local tumor FasL expression, increases CD8 +Fas + T cell infiltration, and decreases tumor volume in pancreatic neuroendocrine tumor models. Kp7-6 prevents concanavalin A-induced liver injury in mice. Kp7-6 is applicable to research related to type 2 diabetes, concanavalin A-induced hepatitis and pancreatic neuroendocrine tumors .
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Cat. No.: HY-P991015
CAS No.: 2921676-04-0
Synonyms: JNJ-78278343; KLCB-245

Target:  

CD3

Research Areas:  

Cancer

Pasritamig (JNJ-78278343; KLCB-245) is a bispecific T-cell engager (BiTE) that targets the complex of human kallikrein KLK2 and CD3 receptor. Pasritamig redirects the cytotoxicity of T cells to KLK2-expressing tumor cells and induces T cell-mediated lysis of KLK2-expressing prostate cancer cells. Administered via subcutaneous injection, subcutaneous infusion or intravenous infusion, Pasritamig exhibits antitumor activity against metastatic castration-resistant prostate cancer. Pasritamig has a safety profile with an extremely low incidence of cytokine release syndrome and can be safely administered in an outpatient setting. Pasritamig is applicable to the research of metastatic castration-resistant prostate cancer .
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Cat. No.: HY-P0277
CAS No.: 168635-85-6
Synonyms: CEA peptide
Carcinoembryonic antigen peptide 1 (CEA peptide) is a 9-amino acid HLA-A0201-binding cytotoxic T lymphocyte (CTL) epitope peptide derived from carcinoembryonic antigen (CEA). The IC50 of Carcinoembryonic antigen peptide 1 binding to HLA-A0201 is 2 μM. Carcinoembryonic antigen peptide 1 binds to HLA-A0201 to form a peptide-MHC I complex, which is recognized by the T cell receptor (TCR) of CAP1-specific CD8 + CTLs, thereby inducing antigen-specific T cell activation, IFN-γ production, and CTL-mediated lysis of target cells. Carcinoembryonic antigen peptide 1 is used in research on CEA-specific CTL responses and colorectal cancer .
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Cat. No.: HY-P991201

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

REGN-7257 is a humanized monoclonal antibody targeting IL2RG. REGN-7257 blocks the signal transduction induced by common gamma chain (γc) cytokines via the IL2RG chain of the γc cytokine receptor complex. REGN-7257 is applicable for research on immune-mediated diseases and T cell-mediated diseases . Its corresponding isotype control is Human IgG4 kappa, Isotype Control (HY-P99003).
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Cat. No.: HY-P99837
CAS No.: 2367001-71-4
Synonyms: SPV-T3a

Target:  

CD3

Research Areas:  

Infection

Dafsolimab (SPV-T3a) is a Mouse IgG2b monoclonal antibody (anti-CD3). Dafsolimab can induce cell death through modulation and activation of the CD3/T cell receptor complex. Dafsolimab can be used for the research of graft-versus-host disease (GVHD) .
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Cat. No.: HY-P990154
Anti-Mouse TIM-1/CD365 Antibody (3B3) is a rat-derived IgG2a κ type agonistic antibody, targeting to mouse TIM-1/CD365. Anti-Mouse TIM-1/CD365 Antibody (3B3) enhances T-cell proliferation and responses by forming a stable TIM-1 complex and bringing TIM-1 into the T-cell receptor (TCR)-CD3 complex. Anti-Mouse TIM-1/CD365 Antibody (3B3) can be used for the researches of cancer, inflammation and immunology, such as experimental autoimmune encephalomyelitis, B16 F10 tumor and transplant .
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Cat. No.: HY-157288
Research Areas:  

Metabolic Disease

(R)-Phe-A110/B319, a hapten, is a selective binder to tumor-associated antigens. (R)-Phe-A110/B319 has a 20-fold higher affinity towards the H1047R mutant of p110α in the p110α/p85α PI3K complex. (R)-Phe-A110/B319 can be used for the research of conditional chimeric antigen receptor T (CAR-T) cell activation and tumor targeting .
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Cat. No.: HY-P10525
CAS No.: 167278-49-1
Target:  

Inhibitory Antibodies

Research Areas:  

Neurological Disease

MBP Ac1-9 (4Y) is a synthetic peptide derived from a fragment of myelin basic protein (MBP) that has undergone specific chemical modifications. MBP Ac1-9 (4Y) is able to form a complex with the MHC class II molecule I-Au and activate specific T cell receptor (TCR), thus playing a role in the pathogenesis of experimental autoimmune encephalomyelitis (EAE). MBP Ac1-9 (4Y) can be used to study autoimmune diseases, especially those involving the central nervous system, such as multiple sclerosis .
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Cat. No.: HY-P78753
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD3G; T3G; CD3 Gamma Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Gamma Subunit Of T3; T-cell Surface Glycoprotein CD3 Gamma Chain; CD3g Molecule, Epsilon (CD3-TCR complex); T-cell receptor T3 Gamma Chain; TCR Ti Gamma-Chain V8-J2
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P71845
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD3G; T3G; CD3 Gamma Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Gamma Subunit Of T3; T-cell Surface Glycoprotein CD3 Gamma Chain; CD3g Molecule, Epsilon (CD3-TCR complex); T-cell receptor T3 Gamma Chain; TCR Ti Gamma-Chain V8-J2
Species:  
Cynomolgus
Source:  
P. pastoris
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Cat. No.: HY-P705116
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex); CD3G; T3G; CD3 Gamma Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Gamma Subunit Of T3; T-cell Surface Glycoprotein CD3 Gamma Chain; CD3g Molecule, Epsilon (CD3-TCR complex); T-cell receptor T3 Gamma Chain; TCR Ti Gamma-Chain V8-J2 Region; CD3-GAMMA; TCR Ti Gamma-Chain V9-J2 Region; CD3GAMMA; CD3g Molecule; CD3g Antigen, Gamma Polypeptide (TiT3 complex); CD3g Antigen; CD3g Molecule, Gamma (CD3-TCR complex); IMD17
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P70506
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex)
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P78874
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex)
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P72899
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex); CD3G; T3G; CD3 Gamma Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Gamma Subunit Of T3; T-cell Surface Glycoprotein CD3 Gamma Chain; CD3g Molecule, Epsilon (CD3-TCR complex); T-cell receptor T3 Gamma Chain; TCR Ti Gamma-Chain V8-J2 Region; CD3-GAMMA; TCR Ti Gamma-Chain V9-J2 Region; CD3GAMMA; CD3g Molecule; CD3g Antigen, Gamma Polypeptide (TiT3 complex); CD3g Antigen; CD3g Molecule, Gamma (CD3-TCR complex); IMD17
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P75415
Purity:  ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex)
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P76802
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex)
Species:  
Rhesus Macaque
Source:  
HEK293
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Cat. No.: HY-P704321
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex)
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P77604
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex)
Species:  
Cynomolgus
Source:  
HEK293
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Cat. No.: HY-P704463
Purity:  /
Synonyms: Mafa-AG; MHC class I antigen; CD3E; T3E; CD3 Epsilon Subunit Of T-cell receptor complex; T-cell Antigen receptor complex, Epsilon Subunit Of T3; T-cell Surface Glycoprotein CD3 Epsilon Chain; CD3e Molecule; CD3-Epsilon; CD3e Antigen; CD3epsilon; CD3E Protein; CD3e Antigen, Epsilon Polypeptide (TiT3 complex); IMD18; T-cell Surface Antigen T3/Leu-4 Epsilon Chain; TCRE; CD3e Molecule, Epsilon (CD3-TCR complex)
Species:  
Human
Source:  
HEK293
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