55 Results for "

T7

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "T7" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-115400
CAS No.: 1062444-54-5
Purity:  99.67%
Synonyms: TLR7 agonist T7
Research Areas:  

Cancer

1V209 (TLR7 agonist T7) is a Toll-like receptor 7 (TLR7) agonist and has anti-tumor effects. 1V209 can be conjugated with various polysaccharides to improve its water solubility, and enhance its efficacy, and maintain low toxicity .
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1
1 Cited Publications
Cat. No.: HY-111815A
CAS No.: 2803886-33-9
Purity:  99.91%
Synonyms: ac4CTP sodium solution (100mM)
Target:  

Endogenous Metabolite

Research Areas:  

Others

N4-Acetylcytidine triphosphate sodium solution (100mM) is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription and it can be incorporated into multiple templates .
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1
1 Cited Publications
Cat. No.: HY-P0327
CAS No.: 245445-88-9
Target:  

Inhibitory Antibodies

Research Areas:  

Others

T7 Tag Peptide is a protein tag peptide composed of 11 residues from the N-terminus of gp10, the capsid protein of T7 bacteriophage. T7 Tag Peptide can be fused to the N-terminus or C-terminus of proteins such as enhanced green fluorescent protein (EGFP). T7 Tag Peptide is applicable for various immunoassays and affinity purification .
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1
1 Cited Publications
Cat. No.: HY-P0327A
Target:  

Inhibitory Antibodies

Research Areas:  

Others

T7 Tag Peptide TFA is a protein tag consisting of 11 residues from the N-terminus of the T7 bacteriophage capsid protein gp10. T7 Tag Peptide TFA can be fused to the N-terminus or C-terminus of proteins such as enhanced green fluorescent protein (EGFP). T7 Tag Peptide TFA can be used in various immunoassays and affinity purification .
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1
1 Cited Publications
Cat. No.: HY-P71109
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ODC1; Alternative Protein ODC1; Ornithine Decarboxylase 1; NEDBIA; ODC; NEDBA; Ornithine Decarboxylase; BABS
Species:  
Human
Source:  
E. coli
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Cat. No.: HY-163028
CAS No.: 459789-75-4
Target:  

Tim3

Research Areas:  

Cancer

ML-T7 is a potent Tim-3 inhibitor. ML-T7 blocks Tim-3 interactions with PtdSer and CEACAM1. ML-T7 not only enhances the antitumor activity of adoptive transfer therapy with cytotoxic T lymphocytes (CTLs) and CAR T cells but also increases the effector function of T cell. ML-T7 promotes NK cells’ killing activity against tumor cells and DC antigen-presenting capacity. ML-T7 directly exerts antitumor efficacy in preclinical tumor models either alone or in combination with Nivolumab (HY-P9903A). ML-T7 can be used for tumor immunotherapy research .
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Cat. No.: HY-172723
Research Areas:  

Neurological Disease Cancer

DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes, where liposomes modified with both T7 and DA7R peptides can effectively co-deliver Doxorubicin (HY-15142A) and Vincristine (HY-N0488A) to gliomas. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists for synergistic intervention in Parkinson's disease .
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Cat. No.: HY-112624T
CAS No.: 9004-54-0
Synonyms: Dextran 7; Dextran D7; Dextran T7(MW 5600-8400)
Dextran T7 (Dextran 7; Dextran D7) (MW 7,000) is a polymer of anhydroglucose with the average molecular weight of 7000. Dextran T7 (MW 7,000) exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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Cat. No.: HY-E70090
CAS No.: 9014-24-8
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+, T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter .
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Cat. No.: HY-P10323
Synonyms: Tumstatin (74-98), human
Target:  

Integrin FAK mTOR Apoptosis

Research Areas:  

Cancer

T7 Peptide is a protein synthesis inhibitor and anti-angiogenic agent, with a Kd of 10 nM for human transferrin receptor. T7 Peptide inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of 4E-BP1 in endothelial cells. T7 Peptide induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma .
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Cat. No.: HY-P10323A
Synonyms: Tumstatin (74-98), human TFA
Target:  

Integrin FAK mTOR Apoptosis

Research Areas:  

Cancer

T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a Kd of 10 nM for human transferrin receptor. T7 Peptide TFA inhibits the phosphorylation of focal adhesion kinase, the activation of phosphatidylinositol 3-kinase and Akt, the kinase activity of mTOR, as well as the phosphorylation of 4E-BP1 in endothelial cells. T7 Peptide TFA induces G0/G1 cell cycle arrest, apoptosis and protective autophagy in hepatocellular carcinoma cells, and suppresses tumor growth in mouse models. T7 Peptide TFA is applicable to research related to cancer, glioblastoma, hepatocellular carcinoma and glioma .
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Cat. No.: HY-112581B
Purity:  99.89%
Synonyms: 5-Methoxy-UTP trisodium solution (100 mM); 5-OMe-UTP trisodium solution (100 mM)
5-Methoxyuridine 5'-triphosphate trisodium solution (100 mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase .
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Cat. No.: HY-158772
Purity:  99.6%
Target:  

DNA/RNA Synthesis

Research Areas:  

Others

m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) is a trinucleotide cap analog with a Cap1 structure. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) can be co-transcriptionally incorporated into the 5' end of mRNA during T7 RNA polymerase-mediated in vitro transcription to form a natural Cap1 cap structure. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) enhances mRNA translation efficiency and reduces innate immune recognition, and it has been used in the preparation of self-amplifying mRNA rabies vaccines. m7G(5')ppp(5')(2'OMeA)pU (ammonium) solution (100 mM) can be applied to research related to in vitro mRNA transcription and mRNA vaccines .
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Cat. No.: HY-P0329
CAS No.: 339988-16-8
Target:  

Inhibitory Antibodies

Research Areas:  

Others

X-press Tag Peptide is a tag peptide used for protein purification. X-press Tag is also an N-terminal leader peptide; this N-terminal peptide contains a polyhistidine sequence, the Xpress epitope (part of bacteriophage T7 gene 10 protein) and an enterokinase cleavage site. Anti-Xpress antibodies recognize the Xpress epitope sequence found in this leader peptide.
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Cat. No.: HY-E70400
Target:  

DNA/RNA Synthesis

Research Areas:  

Infection

Thermostable T7 RNA Polymerase is a thermostable version of T7 RNA Polymerase (HY-E70090). Compared with T7 RNA Polymerase, it has high temperature resistance and stable activity. T7 RNA polymerase is a polymerase expressed by Escherichia coli from the RNA polymerase gene of T7 bacteriophage. T7 RNA polymerase is highly specific and involved in in vitro transcription (IVT) of mRNA. In the presence of Mg 2+, T7 RNA polymerase only uses the single-stranded or double-stranded DNA containing the T7 promoter sequence as a template, and uses NTP as a substrate to synthesize RNA complementary to the single-stranded DNA downstream of the promoter .
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Cat. No.: HY-111815
CAS No.: 1428903-57-4
Synonyms: ac4CTP
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

N4-Acetylcytidine triphosphate is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription and can be incorporated into multiple templates .
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Cat. No.: HY-131740
CAS No.: 67460-15-5
Synonyms: C7dATP
2'-Deoxytubercidin 5'-triphosphate (C7dATP) is a deoxyadenosine triphosphate (dATP) analog that serves as a substrate for DNA polymerases. 2'-Deoxytubercidin 5'-triphosphate eliminates Hoogsteen base-pairing capacity and weakens base-stacking interactions; it is recognized and incorporated into nascent DNA strands by DNA polymerases such as Klenow and T7; it reduces DNA electrophoresis compression artifacts; it is effectively degraded by apyrase, thereby lowering the enzyme product inhibition effect caused by dATPaS. 2'-Deoxytubercidin 5'-triphosphate reduces abnormal electrophoretic mobility caused by compression of G or A residues and is used to improve the quality of DNA sequencing data .
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Cat. No.: HY-184387
CAS No.: 2552327-34-9
Target:  

Bacterial

Research Areas:  

Infection

Pleuromutilin conjugate T7 is a broad-spectrum antibacterial agent. Pleuromutilin conjugate T7 inhibits bacterial energy uptake, reverses drug efflux, interferes with carbohydrate metabolism, inhibits protein synthesis, disrupts biofilms, impairs cell membrane integrity, and attenuates the functions of virulence and adhesion factors. Pleuromutilin conjugate T7 can be used in studies related to Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) infections, multidrug-resistant Enterococcus faecalis infections, and Gram-negative bacterial infections .
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Cat. No.: HY-172722
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG1000-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG1000-T7 can be used for drug delivery .
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Cat. No.: HY-172723A
Target:  

Liposome

Research Areas:  

Cancer

DSPE-PEG3400-T7 is a PEG compound which composed of DSPE and a transferrin receptor (TfR) peptide (T7). T7 (HAIYPRH) specifically binds to TfR (transferrin receptor). DSPE-PEG3400-T7 can be used for drug delivery .
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