10219 Results for "

TACK activity

" in MedChemExpress (MCE) Product Catalog:
Products (10219)

10219 Results for "TACK activity" in MCE Product Catalog:

784
Acetylcysteine
Acetylcysteine
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784 Publications Verification
Cat. No.: HY-B0215
CAS No.: 616-91-1
Synonyms: N-Acetylcysteine; N-Acetyl-L-cysteine; NAC
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Reactive Oxygen Species (ROS) Endogenous Metabolite Apoptosis Ferroptosis Influenza Virus Disulfidptosis

Acetylcysteine (N-Acetylcysteine) is a mucolytic agent that can cross the blood-brain barrier, which reduces the thickness of the mucus. Acetylcysteine is a ROS inhibitor. Acetylcysteine is a cysteine precursor, prevents hemin-induced ferroptosis by neutralizing toxic lipids generated by arachidonate-dependent activity of 5-lipoxygenases. Acetylcysteine induces cell apoptosis. Acetylcysteine also has anti-influenza virus activities. In addition, Acetylcysteine ​​is the most stable form of cysteine ​​during drug delivery and can be used in disulfidptosis studies .
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466
Deferoxamine mesylate
Deferoxamine mesylate
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466 Cited Publications
Cat. No.: HY-B0988
CAS No.: 138-14-7
Synonyms: Desferrioxamine B mesylate; DFOM
Target:  

Autophagy HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Apoptosis Akt

Research Areas:  

Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Deferoxamine mesylate (Deferoxamine B mesylate) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine mesylate upregulates HIF-1α levels with good antioxidant activity. Deferoxamine mesylate also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine mesylate can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 .
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466
Deferoxamine
Deferoxamine
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466 Cited Publications
Cat. No.: HY-B1625
CAS No.: 70-51-9
Synonyms: Deferoxamine B; Deferriferrioxamine B; Deferrioxamine
Target:  

HIF/HIF Prolyl-Hydroxylase Reactive Oxygen Species (ROS) Apoptosis Akt Autophagy

Research Areas:  

Infection Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Deferoxamine (Deferoxamine B) is an iron chelator (binds to Fe(III) and many other metal cations), is widely used to reduce iron accumulation and deposition in tissues. Deferoxamine upregulates HIF-1α levels with good antioxidant activity. Deferoxamine also shows anti-proliferative activity, can induce apoptosis and autophagy in cancer cells. Deferoxamine can be used in studies of diabetes, neurodegenerative diseases as well as anti-cancer and anti-COVID-19 .
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202
Doxycycline
Doxycycline
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202 Cited Publications
Cat. No.: HY-N0565
CAS No.: 564-25-0
Target:  

MMP Bacterial Antibiotic Parasite

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .
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202
Doxycycline hydrochloride
Doxycycline hydrochloride
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202 Cited Publications
Cat. No.: HY-N0565A
CAS No.: 10592-13-9
Target:  

MMP Bacterial Antibiotic Parasite

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hydrochloride can be used to construct gene expression regulation models .
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202
Doxycycline hyclate
Doxycycline hyclate
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202 Cited Publications
Cat. No.: HY-N0565B
CAS No.: 24390-14-5
Synonyms: Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031
Target:  

Antibiotic MMP Bacterial Parasite

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hyclate can be used to construct gene expression regulation models .
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135
Imatinib
Imatinib
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135 Cited Publications
Cat. No.: HY-15463
CAS No.: 152459-95-5
Purity:  99.95%
Synonyms: STI571; CGP-57148B
Target:  

Bcr-Abl PDGFR c-Kit SARS-CoV Autophagy

Research Areas:  

Cancer

Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively . Imatinib also is an inhibitor of SARS-CoV and MERS-CoV .
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118
Talazoparib
Talazoparib
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118 Cited Publications
Cat. No.: HY-16106
CAS No.: 1207456-01-6
Synonyms: BMN-673; LT-673
Target:  

PARP

Research Areas:  

Cancer

Talazoparib (BMN-673) is a highly potent, orally active PARP1/2 inhibitor.Talazoparib inhibits PARP1 and PARP2 enzyme activity with Kis of 1.2 nM and 0.87 nM, respectively. Talazoparib has antitumor activity .
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109
Pifithrin-α hydrobromide
Pifithrin-α hydrobromide
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109 Cited Publications
Cat. No.: HY-15484
CAS No.: 63208-82-2
Purity:  98.58%
Synonyms: Pifithrin hydrobromide; PFTα hydrobromide
Target:  

MDM-2/p53 Aryl Hydrocarbon Receptor Ferroptosis Apoptosis

Research Areas:  

Cancer

Pifithrin-α hydrobromide is a p53 inhibitor which blocks its transcriptional activity and prevents cells from apoptosis. Pifithrin-α hydrobromide is also an aryl hydrocarbon receptor (AhR) agonist.
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99
Nicotinamide
Nicotinamide
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99 Cited Publications
Cat. No.: HY-B0150
CAS No.: 98-92-0
Synonyms: Niacinamide; Nicotinic acid amide
Category:  

Alkaloids Human Gut Microbiota Metabolites Microorganisms Neurological Disease Pyridine Alkaloids Endogenous metabolite Disease Research Fields Cancer

Target:  

Environmental Pollutants Endogenous Metabolite Sirtuin HBV Organoid

Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC50: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD+, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity .
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91
Irinotecan hydrochloride trihydrate
Irinotecan hydrochloride trihydrate
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91 Cited Publications
Cat. No.: HY-16568
CAS No.: 136572-09-3
Synonyms: (+)-Irinotecan hydrochloride trihydrate; CPT-11 hydrochloride trihydrate
Target:  

Topoisomerase Autophagy

Research Areas:  

Cancer

Irinotecan hydrochloride trihydrate ((+)-Irinotecan hydrochloride trihydrate) is a topoisomerase I inhibitor with antitumor activity .
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89
Indomethacin
Indomethacin
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89 Cited Publications
Cat. No.: HY-14397
CAS No.: 53-86-1
Purity:  99.91%
Synonyms: Indometacin
Target:  

COX Antibiotic Influenza Virus Bacterial

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research .
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89
Indomethacin sodium hydrate
Indomethacin sodium hydrate
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89 Cited Publications
Cat. No.: HY-14397A
CAS No.: 74252-25-8
Purity:  99.85%
Synonyms: Indometacin sodium hydrate
Target:  

COX Bacterial Influenza Virus Antibiotic

Research Areas:  

Infection Neurological Disease Inflammation/Immunology Cancer

Indomethacin (Indometacin) sodium hydrateis a orally active and BBB-permeable COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin sodium hydrateis has anticancer activity and anti-infective activity. Indomethacin sodium hydrateis can be used for cancer, inflammation and viral infection research .
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86
Cyclophosphamide
Cyclophosphamide
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86 Cited Publications
Cat. No.: HY-17420
CAS No.: 50-18-0
Target:  

DNA Alkylator/Crosslinker

Research Areas:  

Cancer

Cyclophosphamide is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic activity, a immunosuppressant.
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86
Cyclophosphamide hydrate
Cyclophosphamide hydrate
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86 Cited Publications
Cat. No.: HY-17420A
CAS No.: 6055-19-2
Synonyms: Cyclophosphamide monohydrate
Target:  

DNA Alkylator/Crosslinker

Research Areas:  

Cancer

Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.
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84
Pronase E (Activity ≥ 7000 U/g)
Pronase E (Activity ≥ 7000 U/g)
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84 Cited Publications
Cat. No.: HY-114158
CAS No.: 9036-06-0
Synonyms: Pronase (activity ≥ 7000 U/g)
Category:  

Natural Products Microorganisms Other Diseases Disease Research Fields

Target:  

Others

Pronase E (Activity ≥ 7000 U/g) is a mixture of proteolytic enzymes that is obtained from Streptomyces griseus and could digest protein into individual amino acids .
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81
Oxamic acid
Oxamic acid
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81 Cited Publications
Cat. No.: HY-W013032
CAS No.: 471-47-6
Synonyms: Oxamidic acid
Category:  

Natural Products Animals

Target:  

Lactate Dehydrogenase Apoptosis

Oxamic acid is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis .
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81
Oxamic acid sodium
Oxamic acid sodium
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81 Cited Publications
Cat. No.: HY-W013032A
CAS No.: 565-73-1
Synonyms: Sodium oxamate
Target:  

Lactate Dehydrogenase Apoptosis

Research Areas:  

Cancer

Oxamic acid (oxamate) sodium salt is a lactate dehydrogenase-A (LDH-A) inhibitor. Oxamic acid sodium salt shows anti-tumor activity, and anti-proliferative activity against cancer cells, and can induce apoptosis .
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75
Camptothecin
Camptothecin
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75 Cited Publications
Cat. No.: HY-16560
CAS No.: 7689-03-4
Synonyms: Campathecin; (S)-(+)-Camptothecin; CPT
Category:  

Infection Nyssaceae Extract Alkaloids Quinoline Alkaloids 500 - Internal Server Error | MedChemExpress

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