9 Results for "

TAPI

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "TAPI" in MCE Product Catalog:

16
TAPI-1
TAPI-1
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16 Cited Publications
Cat. No.: HY-16657
CAS No.: 163847-77-6
Target:  

MMP NF-κB Apoptosis TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

TAPI-1 is a broad-spectrum MMP inhibitor and NF-κB p65 inhibitor that targets ADAM17/TACE, ADAM10 and other proteins. TAPI-1 reduces the proteolytic cleavage of membrane-bound TNF-α, decreases TNF-α levels, inhibits NF-κB pathway activation, and downregulates profibrotic markers. TAPI-1 reduces the proportion of proinflammatory immune cells, alleviates cardiac and airway fibrosis, and improves cardiac function after myocardial infarction. Meanwhile, TAPI-1 inhibits the viability, migration and invasion of esophageal squamous cell carcinoma cells, enhances the chemosensitivity of Cisplatin (HY-17394), induces apoptosis, and shows low toxicity to normal esophageal epithelial cells. TAPI-1 can be widely used in studies related to myocardial infarction-induced heart failure, severe traumatic tracheal stenosis, esophageal squamous cell carcinoma and other conditions .
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6
TAPI-2
TAPI-2
0 Images
6 Cited Publications
Cat. No.: HY-100211
CAS No.: 187034-31-7
Purity:  97.41%
Synonyms: TNF Protease Inhibitor 2
Target:  

MMP SARS-CoV

Research Areas:  

Cancer

TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
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(S,S)-TAPI-1
(S,S)-TAPI-1
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Cat. No.: HY-16657A
CAS No.: 171235-71-5
Target:  

MMP mAChR

Research Areas:  

Neurological Disease Inflammation/Immunology Cancer

(S,S)-TAPI-1 is an isomer of TAPI-1. TAPI-1 is a TACE (ADAM17) inhibitor and blocks the shedding of several cell surface proteins. TAPI-1 is also a metalloproteinase (MMP) inhibitor .
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TAPI-0
TAPI-0
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Cat. No.: HY-118694
CAS No.: 163958-73-4
Purity:  98.98%
Target:  

TNF Receptor MMP Bacterial

Research Areas:  

Infection Cancer

TAPI-0 is a TACE (TNF-α converting enzyme; ADAM17) inhibitor with an IC50 of 100 nM. TAPI-0 is a MMP inhibitor and also attenuates TNF-α processing .
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(S,S)-TAPI-0
(S,S)-TAPI-0
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Cat. No.: HY-136885
CAS No.: 143457-40-3
Target:  

MMP

Research Areas:  

Infection

(S,S)-TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S,S)-TAPI-0 can be used to study Chlamydia infection .
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Tetrapropylammonium iodide
Tetrapropylammonium iodide
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Cat. No.: HY-W009202
CAS No.: 631-40-3
Synonyms: TAPI
Tetrapropylammonium iodide is an organic compound commonly used as ionic liquids and catalysts. It can be used as a solvent in some chemical reactions, and can also be used as a catalyst to promote some organic synthesis reactions. In addition, the compound is also widely used in batteries, solar cells and pigments.
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(R)-TAPI-2
(R)-TAPI-2
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Cat. No.: HY-100211A
CAS No.: 689284-12-6
Synonyms: (R)-TNF Protease Inhibitor 2
Target:  

SARS-CoV MMP

Research Areas:  

Cancer

(R)-TAPI-2 is the isomer of TAPI-2 (HY-100211A). TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
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Goniopypyrone
Goniopypyrone
0 Images
Cat. No.: HY-N3967
CAS No.: 129578-07-0
Synonyms: (+)-Goniopypyrone
Category:  

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