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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
TBP-EQ
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "TBP-EQ" in MCE Product Catalog:
Cat. No.: HY-189567
Research Areas:
TBP-EQ is a cationic aggregation-induced emission photosensitizer and luminogen that enables bright red aggregation-state fluorescence imaging. TBP-EQ generates reactive oxygen species (ROS) via Type I/II pathways under light irradiation. TBP-EQ undergoes light-triggered translocation from the plasma membrane to mitochondria, enhancing penetration and mitochondrial enrichment, and induces oxidative plasma membrane damage, increased permeability, as well as mitochondrial oxidative stress, dysfunction, and depolarization. TBP-EQ exhibits photodynamic cytotoxicity against breast cancer cells, and intratumoral injection followed by light activation inhibits tumor growth. TBP-EQ preferentially accumulates in breast cancer cells and prolongs tumor retention while reducing off-target fluorescence. TBP-EQ can be used for breast cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
