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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
TCP
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "TCP" in MCE Product Catalog:
7
7 Publications Verification
Cat. No.: HY-P70450
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL5; T-Cell Specific Protein P288; Prev. D17S136E; C-C Motif Chemokine 5; Prev. SCYA5; MGC17164; TCP228; EoCP; SIS-Delta; Small Inducible Cytokine A5 (RANTES); RANTES; T-Cell Specific RANTES Protein; SISd; T-Cell-Specific Protein RANTES; Regulated Upon Activation, Normally T-Expressed, And Presumably Secreted; T Cell-Specific Protein P228; Small Inducible Cytokine Subfamily A (Cys-Cys), Member 5; Small-Inducible Cytokine A5; Eosinophil Chemotactic Cytokine; C-C Motif Chemokine; Chemokine (C-C Motif) Ligand 5; C-C Motif Chemokine Ligand 5; Beta-Chemokine RANTES
Species:
Human
Source:
E. coli
4
4 Cited Publications
Cat. No.: HY-P71890
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL5; T-Cell Specific Protein P288; Prev. D17S136E; C-C Motif Chemokine 5; Prev. SCYA5; MGC17164; TCP228; EoCP; SIS-Delta; Small Inducible Cytokine A5 (RANTES); RANTES; T-Cell Specific RANTES Protein; SISd; T-Cell-Specific Protein RANTES; Regulated Upon A
Species:
Mouse
Source:
E. coli
3
3 Cited Publications
Target:
Research Areas:
HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1) . HSF1A also acts as a specific inhibitor of TRiC/CCT. Chaperonin TCP-1 ring complex (TRiC)/chaperonin containing TCP-1 (CCT) plays a pivotal role in toxin translocation and/or refolding .
2
2 Cited Publications
Cat. No.: HY-P7282
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CCL5; T-Cell Specific Protein P288; Prev. D17S136E; C-C Motif Chemokine 5; Prev. SCYA5; MGC17164; TCP228; EoCP; SIS-Delta; Small Inducible Cytokine A5 (RANTES); RANTES; T-Cell Specific RANTES Protein; SISd; T-Cell-Specific Protein RANTES; Regulated Upon A
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P71053
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: SPINK1; PCTT; Serine Peptidase Inhibitor Kazal Type 1; Serine Protease Inhibitor, Kazal Type 1; PSTI; Serine Protease Inhibitor Kazal-Type 1; TATI; Tumor-Associated Trypsin Inhibitor; Pancreatic Secretory Trypsin Inhibitor; TCP; Spink3
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P702493
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SPINK1; PCTT; Serine Peptidase Inhibitor Kazal Type 1; Serine Protease Inhibitor, Kazal Type 1; PSTI; Serine Protease Inhibitor Kazal-Type 1; TATI; Tumor-Associated Trypsin Inhibitor; Pancreatic Secretory Trypsin Inhibitor; TCP; Spink3
Species:
Mouse
Source:
P. pastoris
Synonyms: SD-142
Target:
Research Areas:
EpoY (SD-142) acts as an irreversible inhibitor of the brain's primary tubulin tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP). By inhibiting TCP with an IC50 value of approximately 500 nM, EpoY effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation. This inhibition leads to significant differentiation defects and has been linked to underlying issues associated with cancer and cardiomyopathies.
Target:
Research Areas:
S2116, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2116 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2116 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2116 significantly retardes the growth of T-ALL cells in xenotransplanted mice .
Target:
Research Areas:
S2157, a N-alkylated tranylcypromine (TCP) derivative, is a potent lysine-specific demethylase 1 (LSD1) inhibitor. S2157 increases H3K9 methylation and reciprocal H3K27 deacetylation at super-enhancer regions. S2157 induces apoptosis in TCP-resistant T-cell acute lymphoblastic leukemia (T-ALL) cells by repressing transcription of the NOTCH3 and TAL1 genes. S2157 efficiently pass through the blood-brain barrier and can almost completely eradicate CNS leukemia in mice transplanted with T-ALL cells .
Cat. No.: HY-108668
CAS No.: 873398-67-5
Target:
Research Areas:
TC-P 262 is a potent P2X3 inhibitor. TC-P 262 shows inhibition by bindings to hP2X3. TC-P 262 has the potential for the research of rheumatoid arthritis, cough, and pain .
Cat. No.: HY-D1420
Target:
Research Areas:
TCP-BP-SFAC is a luminogenic molecule. TCP-BP-SFAC exhibits strong sky-blue delayed fluorescence in neat films, with photoluminescence (PL) peaks at ~483 nm and delayed fluorescence lifetimes of 5.4 to 5.7 μs .
Cat. No.: HY-161848
Target:
Research Areas:
TCP-MP-CA (compound 11a) is an inhibitor of LSD1 demethylation enzymatic via binding to LSD1/CoREST complex. TCP-MP-CA exhibits an inhibitory effect on osteoclastogenesis, with an IC50 value of 0.14 µM .
Cat. No.: HY-RS14321
Target:
Research Areas:
TCP1 Human Pre-designed siRNA Set A contains three designed siRNAs for TCP1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14322
Target:
Research Areas:
TCP11 Human Pre-designed siRNA Set A contains three designed siRNAs for TCP11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14324
Target:
Research Areas:
TCP11L2 Human Pre-designed siRNA Set A contains three designed siRNAs for TCP11L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P3319
CAS No.: 127634-29-1
Target:
Research Areas:
Cat. No.: HY-RS13679
Target:
Research Areas:
SPINK1 Human Pre-designed siRNA Set A contains three designed siRNAs for SPINK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19962
Target:
Research Areas:
Tcp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tcp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS26464
Target:
Research Areas:
Tcp1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tcp1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS14323
Target:
Research Areas:
TCP11L1 Human Pre-designed siRNA Set A contains three designed siRNAs for TCP11L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
