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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
TIR1
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "TIR1" in MCE Product Catalog:
20
20 Cited Publications
Target:
Research Areas:
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression.
7
7 Cited Publications
Synonyms: 2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid
Target:
Research Areas:
PEO-IAA is an indole-3-acetic acid (IAA) antagonist. PEO-IAA is an auxin antagonist that binds to transport inhibitor response 1/auxin signaling F-box proteins (TIR1/AFBs).
Cat. No.: HY-113851
CAS No.: 1020201-82-4
Target:
Research Areas:
BH-IAA is a potent auxin antagonist that specifically blocks TIR1-mediated auxin signaling [1].
Cat. No.: HY-B0868
CAS No.: 25168-26-7
2,4-D isooctyl ester, a synthetic auxin herbicide, is a TIR1 protein transport inhibitor. 2,4-D isooctyl ester interacts with TIR1 to facilitate auxin signal transduction, activating auxin-mediated growth responses. 2,4-D isooctyl ester functions as a pro-herbicide bio-transformed into phytotoxic 2,4-D post-plant absorption, disrupting normal plant growth. 2,4-D isooctyl ester can be used to control broadleaf weeds [1] .
Cat. No.: HY-P10229
Target:
Research Areas:
Cat. No.: HY-111444R
CAS No.: 86445-22-9
Target:
Research Areas:
Auxinole (Standard) is the analytical standard of Auxinole (HY-111444). This product is intended for research and analytical applications. Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex and so inhibits auxin-responsive gene expression.
Cat. No.: HY-187762
CAS No.: 868215-90-1
Synonyms: F1800-0169
Target:
Research Areas:
AAL1 is a synthetic auxin analog with weak auxin activity, which acts through the auxin receptor TIR1. AAL1 inhibits root and hypocotyl growth of dark-grown Arabidopsis thaliana seedlings, with growth inhibition IC50 values of approximately 20 μM and 50 μM, respectively. AAL1 activates the auxin signaling pathway, promotes DII-VENUS degradation and auxin-responsive gene expression, and its biological effects depend on the auxin influx and efflux transport systems. AAL1 can be used to study weak genetic interactions in the auxin signaling pathway and the regulation of auxin function by amino acids [1].
Cat. No.: HY-P702882
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SARM1; Sterile Alpha And Armadillo Repeat Protein; Sterile Alpha And TIR Motif Containing 1; SAM Domain-Containing Protein 2; SAMD2; TIR-1 Homolog; SARM; NADase SARM1; Sterile Alpha And TIR Motif-Containing Protein 1; MyD88-5; NADP(+) Hydrolase SARM1; HSA
Species:
Human
Source:
HEK293
Cat. No.: HY-P705957
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SARM1; Sterile Alpha And Armadillo Repeat Protein; Sterile Alpha And TIR Motif Containing 1; SAM Domain-Containing Protein 2; SAMD2; TIR-1 Homolog; SARM; NADase SARM1; Sterile Alpha And TIR Motif-Containing Protein 1; MyD88-5; NADP(+) Hydrolase SARM1; HSA
Species:
Human
Source:
HEK293
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
