47 Results for "

TNFRSF17

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "TNFRSF17" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P9980
CAS No.: 2061894-48-0
Synonyms: GSK2857914

Research Areas:  

Cancer

Belantamab (GSK2857916) is a humanized IgG1 anti-BCMA/TNFRSF17 monoclonal antibody. Belantamab is linked to MMAF (HY-15579) through a non-cleavable ADC linker to synthesize the antibody-active molecule conjugate (ADC) Belantamab mafodotin (HY-P3239). After binding to BCMA on the surface of tumor cells, Belantamab mafodotin enters the cell through receptor-mediated endocytosis. After entering the cell, Belantamab mafodotin releases MMAF, blocks cell division by inhibiting tubulin polymerization, arrests the cell cycle and induces cell apoptosis. Belantamab can be used for the study of multiple myeloma, especially relapsed/refractory multiple myeloma .
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1
1 Cited Publications
Cat. No.: HY-P78070
Purity:  ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B Cell Maturation Antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-Cell Maturation Factor; B-Cell Maturation Protein; CD269 Antigen; TNF Receptor
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P99909
CAS No.: 2408850-14-4
Synonyms: PF-06863135; RN-613

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Elranatamab (PF-06863135) is an anti-CD3E/TNFRSF17 human IgG2κ monoclonal antibody . Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002).
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Cat. No.: HY-P991155
CAS No.: 2988886-91-3
Synonyms: JNJ-79635322; JNJ-5322

Target:  

CD3 TNF Receptor

Research Areas:  

Cancer

Ramantamig (JNJ-79635322) is a humanized monoclonal antibody targeting human CD3ε, GPRC5D, and TNFRSF17 (BCMA). Ramantamig binds to BCMA and GPRC5D on multiple myeloma cells, binds to CD3ε on T cells, forms immunological synapses, and enables T-cell-mediated cytotoxicity. Ramantamig activates T cells concomitantly with inducing myeloma cell cytotoxicity, with no nonspecific T-cell activation in the absence of target myeloma cells. Ramantamig carries mutations to reduce interaction with Fc receptors and disrupt protein A binding of monomeric and homodimerized chains. Ramantamig can be used for the research of multiple myeloma .
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Cat. No.: HY-P9980A
Research Areas:  

Cancer

Belantamab (FUT8-KO) is an anti-BCMA (TNFRSF17) monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Belantamab (FUT8-KO) can be used to synthesize antibody-active molecule conjugate (ADC), Belantamab mafodotin .
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Cat. No.: HY-P990686

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

Ispectamab is an anti-TNFRSF17 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-RS14807
Research Areas:  

Others

TNFRSF17 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF17 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-RS16981
Research Areas:  

Others

Tnfrsf17 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf17 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991686
CAS No.: 3038119-48-8

Target:  

TNF Receptor CD3

Research Areas:  

Inflammation/Immunology Cancer

Gamgertamig is a humanized IgG4 bispecific antibody targeting TNFRSF17 & CD3E .
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Cat. No.: HY-P991014
CAS No.: 2925692-65-3

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

HY-P991014 is an TNFRSF17-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P991682
CAS No.: 3037572-57-6
Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

Emzotamig is a bispecific antibody targeting TNFRSF17 and NCR1. Emzotamig is promising for research of autoimmune diseases associated with TNF overexpression, such as rheumatoid arthritis and ankylosing spondylitis .
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Cat. No.: HY-RS23424
Research Areas:  

Others

Tnfrsf17 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf17 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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Cat. No.: HY-P991003
CAS No.: 2839572-09-5

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

HY-P991003 is an TNFRSF17/KLRK1-targeting (G1_L-κ)_(G1-scFvkh_L-κ) type bispecific antibody .
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Cat. No.: HY-P991878

Target:  

TNF Receptor

Research Areas:  

Inflammation/Immunology

TBL-CLN1 is an antibody against human TNFRSF17/BCMA/CD269.
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Cat. No.: HY-P992136
CAS No.: 3075939-10-2

Target:  

CD3

Research Areas:  

Others

Torutamig is a monoclonal antibody targeting TNFRSF17/BCMA/CD269&CD3E .
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Cat. No.: HY-P84468A
Synonyms: BCMA; TNFRSF17; BCM; TNFRSF13A

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84468
Synonyms: BCMA; TNFRSF17; BCM; TNFRSF13A

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P84980
Synonyms: TNFRSF17; BCM; BCMA; Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; CD269 nanobody; BCMA nanobody;

Host:  

Mouse

Application:  

FC, ELISA

Reactivity:  

Human

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Cat. No.: HY-P704268
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B Cell Maturation Antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-Cell Maturation Factor; B-Cell Maturation Protein; CD269 Antigen; TNF Receptor
Species:  
Mouse
Source:  
HEK293
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Cat. No.: HY-P78601
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF17; TNFRSF13A; Prev. BCMA; Tumor Necrosis Factor Receptor Superfamily, Member 17; BCM; B Cell Maturation Antigen; Tumor Necrosis Factor Receptor Superfamily Member 17; B-Cell Maturation Factor; B-Cell Maturation Protein; CD269 Antigen; TNF Receptor
Species:  
Rabbit
Source:  
HEK293
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