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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
TPE-SQ5
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "TPE-SQ5" in MCE Product Catalog:
Cat. No.: HY-D3094
CAS No.: 2687198-42-9
Target:
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TPE-SQ5 is a ratiometric Fluorescent probe for hypochlorite (ClO -) detection with a limit of detection of 5.6 nM. TPE-SQ5 exhibits high selectivity and high sensitivity towards ClO -. TPE-SQ5 can be oxidized by ClO - to form an epoxide, which quenches its deep red fluorescence; subsequently, the epoxide decomposes into a hemicyanine and a sulfonic acid-substituted oxindole, producing blue-green fluorescence to achieve a ratiometric response. TPE-SQ5 can form nanoparticles with Pluronic F-127 via the nanoprecipitation method, and these nanoparticles possess cell permeability. TPE-SQ5 has unique Ex/Em spectra in different solvents and nanoparticle forms, with emission peaks at 643 nm (380 nm excitation, 95% H2O/THF), 631 nm (564 nm excitation, DMSO), 652 nm (536 nm excitation, THF) and 630 nm (524 nm excitation, nanoparticles); the Ex/Em settings used for cell imaging are 488/550-650 nm (red channel) and 405/450-550 nm (green channel) .
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
