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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
21 Results for "
TR3
" in MedChemExpress (MCE) Product Catalog:
Products (21)
21 Results for "TR3" in MCE Product Catalog:
Target:
Research Areas:
THPN is a potent Nur77 agonist. THPN specifically binds the LBD of Nur77 (TR3) but not that of retinoic acid receptor α and PPARγ with a Kd of 270 nM. THPN leads to Nur77 translocation to the mitochondria to induce autophagic cell death in melanoma .
Cat. No.: HY-172769
Target:
Research Areas:
CM112 is a hydrophobic tag-based PRMT1 degrader (DC50 = 0.83 μM) with pan-inhibitory activity against type I PRMTs. CM112 induces proteasome-dependent degradation of PRMT1, inhibits the methyltransferase activities of PRMT1, PRMT3, PRMT4 and PRMT6, downregulates the stability of orphan receptor TR3, thereby interfering with the non-enzymatic scaffolding function of PRMT1. CM112 suppresses clonogenicity and proliferation of tumor cells. CM112 is applicable to research related to breast cancer and non-small cell lung cancer .
Cat. No.: HY-RS09550
Target:
Research Areas:
NR4A1 Human Pre-designed siRNA Set A contains three designed siRNAs for NR4A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16573
Target:
Research Areas:
Nr4a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Nr4a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P85559
Synonyms: mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta; TR-beta; TRXR 2; TRXR2; TRXR2_HUMAN; TXNRD 2; Txnrd2.
Cat. No.: HY-P7S1786
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: NR4A1; Orphan Nuclear Receptor HMR; Prev. GFRP1; Testicular Receptor 3; Prev. HMR; ST-59; NAK-1; Nuclear Receptor Subfamily 4, Group A, Member 1; NGFIB; Growth Factor-Inducible Nuclear Protein N10; NUR77; Steroid Receptor TR3; TR3; TR3 Orphan Receptor; N1
Species:
Human
Source:
E. coli
Cat. No.: HY-RS20613
Target:
Research Areas:
Txnrd2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Txnrd2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15299
Target:
Research Areas:
TXNRD2 Human Pre-designed siRNA Set A contains three designed siRNAs for TXNRD2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P80913
Synonyms: mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta; TR-beta; TRXR 2; TRXR2; TRXR2_HUMAN; TXNRD 2; Txnrd2.
Cat. No.: HY-P80913A
Synonyms: mitochondrial; selenoprotein Z; SELZ; Thioredoxin reductase 2; Thioredoxin reductase 2 mitochondrial; thioredoxin reductase 3; thioredoxin reductase beta; Thioredoxin reductase TR3; TR 3; TR; TR beta; TR-beta; TRXR 2; TRXR2; TRXR2_HUMAN; TXNRD 2; Txnrd2.
Cat. No.: HY-RS14813
Target:
Research Areas:
TNFRSF25 Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF25 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P81717
Synonyms: NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3
Cat. No.: HY-P81717A
Synonyms: NR4A1; GFRP1; HMR; NAK1; Nuclear receptor subfamily 4 group A member 1; Early response protein NAK1; Nuclear hormone receptor NUR/77; Nur77; Orphan nuclear receptor HMR; Orphan nuclear receptor TR3; ST-59; Testicular receptor 3
Cat. No.: HY-P72666
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form; WSL-LR; Apoptosis Inducing Receptor; TRAMP; Death Receptor Beta; WSL-1; Death Receptor 3; APO-3; Protein WSL; TR3; Apo-3; Tumor Necrosis Factor Receptor Superfamily, Member 12 (TRanslocating Chain-Association Membrane Protein); APO3; Tumor Necrosis Factor Receptor Superfamily Member 25; WSL1; Lymphocyte-Associated Receptor Of Death; WSL; Apoptosis-Mediating Receptor TRAMP; TNF Receptor Superfamily Member 25; Apoptosis-Inducing Receptor AIR
Species:
Human
Source:
HEK293
Cat. No.: HY-P704568
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form; WSL-LR; Apoptosis Inducing Receptor; TRAMP; Death Receptor Beta; WSL-1; Death Receptor 3; APO-3; Protein WSL; TR3; Apo-3; Tumor Necrosis Factor Receptor Superfamily, Member 12 (TRanslocating Chain-Association Membrane Protein); APO3; Tumor Necrosis Factor Receptor Superfamily Member 25; WSL1; Lymphocyte-Associated Receptor Of Death; WSL; Apoptosis-Mediating Receptor TRAMP; TNF Receptor Superfamily Member 25; Apoptosis-Inducing Receptor AIR
Species:
Human
Source:
HEK293
Cat. No.: HY-P705014
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: TNFRSF25; Apoptosis-Mediating Receptor DR3; Prev. TNFRSF12; Protein WSL-1; LARD; Tumor Necrosis Factor Receptor Superfamily Member 25 Deletion Mutant; DDR3; Tumor Necrosis Factor Receptor Superfamily, Member 25; DR3; Death Domain Receptor 3 Soluble Form; WSL-LR; Apoptosis Inducing Receptor; TRAMP; Death Receptor Beta; WSL-1; Death Receptor 3; APO-3; Protein WSL; TR3; Apo-3; Tumor Necrosis Factor Receptor Superfamily, Member 12 (TRanslocating Chain-Association Membrane Protein); APO3; Tumor Necrosis Factor Receptor Superfamily Member 25; WSL1; Lymphocyte-Associated Receptor Of Death; WSL; Apoptosis-Mediating Receptor TRAMP; TNF Receptor Superfamily Member 25; Apoptosis-Inducing Receptor AIR
Species:
Human
Source:
HEK293
Cat. No.: HY-RS27121
Target:
Research Areas:
Txnrd2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Txnrd2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19293
Target:
Research Areas:
Tnfrsf25 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tnfrsf25 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
