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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
29 Results for "
TRP-1
" in MedChemExpress (MCE) Product Catalog:
Products (29)
29 Results for "TRP-1" in MCE Product Catalog:
Cat. No.: HY-N2983
CAS No.: 32884-36-9
Category:
Flavonoids Other Diseases Phenols Polyphenols Red seaweeds Leguminosae Extract Plants Disease Research Fields Isoflavones
Target:
Cat. No.: HY-134046
CAS No.: 10391-08-9
Synonyms: Isodocarpin
Category:
Target:
Target:
TSPO TRP Channel Microphthalmia Associated Transcription Factor (MITF) PKC PKA p38 MAPK PERK Interleukin Related
Research Areas:
FGIN-1-27 is a blood-brain barrier-penetrant TSPO ligand with a Ki value of 5 nM. FGIN 1-27 inhibits PKC-β, PKA/CREB, p38/ERK MAPK, MITF, tyrosinase, TRP-1, and TRP-2, thereby inhibiting melanogenesis and pigmentation. FGIN-1-27 alleviates X-ray radiation-induced astrocyte mitochondrial hyperfunction, reduces ROS and superoxide production, inhibits excessive activation of A1-type astrocytes, downregulates GFAP and C3 protein expression, and restores astrocyte proliferative capacity. FGIN-1-27 produces anticonvulsant effects in normal mice; in diazepam-withdrawn mice, the brain MDR pathway becomes subsensitive, and the anticonvulsant activity disappears. FGIN-1-27 attenuates pigmentation in zebrafish embryos and ameliorates UVB-induced skin pigmentation in guinea pigs. FGIN-1-27 directly stimulates testicular Leydig cells while upregulating luteinizing hormone levels, causing an acute increase in serum testosterone in male rats. FGIN 1-27 can be used for research related to hyperpigmentation, epilepsy, brain injury, and other diseases [1] .
Cat. No.: HY-N10016
CAS No.: 132741-56-1
Target:
Cat. No.: HY-N0278A
CAS No.: 90921-11-2
Synonyms: (Rac)-Pulsatilla camphor; (Rac)-Anemonine
Cat. No.: HY-P73568
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TYRP1; tyrosinase related protein 1; TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN; brown; isa; MELANOMA ANTIGEN GP75; 5,6-Dihydroxyindole-2-Carboxylic Acid Oxidase; tyrosinase-related protein 1; TRP-1; Tyrp-1; TYRRP
Species:
Human
Source:
HEK293
Cat. No.: HY-P11636A
Target:
Research Areas:
Cat. No.: HY-P11636
CAS No.: 2844316-27-2
Target:
Research Areas:
Cat. No.: HY-101059R
CAS No.: 142720-24-9
FGIN 1-27 (Standard) is the analytical standard of FGIN 1-27 (HY-101059). This product is intended for research and analytical applications. FGIN-1-27 is a blood-brain barrier-penetrant TSPO ligand with a Ki value of 5 nM. FGIN 1-27 inhibits PKC-β, PKA/CREB, p38/ERK MAPK, MITF, tyrosinase, TRP-1, and TRP-2, thereby inhibiting melanogenesis and pigmentation. FGIN-1-27 alleviates X-ray radiation-induced astrocyte mitochondrial hyperfunction, reduces ROS and superoxide production, inhibits excessive activation of A1-type astrocytes, downregulates GFAP and C3 protein expression, and restores astrocyte proliferative capacity. FGIN-1-27 produces anticonvulsant effects in normal mice; in diazepam-withdrawn mice, the brain MDR pathway becomes subsensitive, and the anticonvulsant activity disappears. FGIN-1-27 attenuates pigmentation in zebrafish embryos and ameliorates UVB-induced skin pigmentation in guinea pigs. FGIN-1-27 directly stimulates testicular Leydig cells while upregulating luteinizing hormone levels, causing an acute increase in serum testosterone in male rats. FGIN 1-27 can be used for research related to hyperpigmentation, epilepsy, brain injury, and other diseases [1] .
Cat. No.: HY-RS18847
Target:
Research Areas:
Tyrp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tyrp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15104
Target:
Research Areas:
TRPC1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11245
Target:
Research Areas:
PRSS1 Human Pre-designed siRNA Set A contains three designed siRNAs for PRSS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15119
Target:
Research Areas:
TRPS1 Human Pre-designed siRNA Set A contains three designed siRNAs for TRPS1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19749
Target:
Research Areas:
Trps1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Trps1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS11645
Target:
Research Areas:
RANBP2 Human Pre-designed siRNA Set A contains three designed siRNAs for RANBP2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
