70 Results for "

TRX

" in MedChemExpress (MCE) Product Catalog:
Products (70)

70 Results for "TRX" in MCE Product Catalog:

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25
NADPH
NADPH
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25 Publications Verification
Cat. No.: HY-113324
CAS No.: 53-57-6
Purity:  99.49%
Category:  

Human Gut Microbiota Metabolites Microorganisms Ketones, Aldehydes, Acids Endogenous metabolite

Target:  

Endogenous Metabolite

NADPH is a coenzyme of glutathione reductase (GR), thioredoxin reductase (TrxR) and NADPH oxidase (NOX), and participates in redox reactions as a hydrogen donor. NADPH has the characteristic of selectively participating in the regulation of cellular redox homeostasis. NADPH exerts antioxidant activity and resists reactive oxygen species (ROS) damage by providing reducing equivalents for the regeneration of glutathione (GSH) and thioredoxin (Trx); at the same time, it acts as a substrate of NOX to generate superoxide anions, mediating oxidative stress and immune response. NADPH participates in maintaining the intracellular reducing environment, biosynthesis and regulating gene expression (such as the Nrf2 pathway), and is mainly used in the study of oxidative stress-related diseases (such as cardiovascular diseases, neurodegenerative diseases, cancer) and immune regulation mechanisms .
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14
PX-12
PX-12
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14 Cited Publications
Cat. No.: HY-13734
CAS No.: 141400-58-0
Purity:  99.87%
Synonyms: IV-2
Target:  

Apoptosis

Research Areas:  

Cancer

PX-12(IV-2) is an irreversible inhibitor of Thioredoxin-1 (Trx-1); inhibits the growth of MCF-7 and HT-29 cells with IC50 values of 1.9 and 2.9 μM, respectively.
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6
Leucomethylene blue mesylate
Leucomethylene blue mesylate
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6 Cited Publications
Cat. No.: HY-19948
CAS No.: 1236208-20-0
Synonyms: TRX0237 mesylate; Methylene blue leuco base mesylate
Leucomethylene blue (TRx0237) mesylate, an orally active second-generation tau protein aggregation inhibitor (Ki of 0.12 μM), could be used for the study of Alzheimer's Disease. Leucomethylene blue mesylate is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes .
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4
TXNIP-IN-1
TXNIP-IN-1
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4 Cited Publications
Cat. No.: HY-115688
CAS No.: 1268955-50-5
Purity:  99.15%
Target:  

Arrestin

Research Areas:  

Cardiovascular Disease Metabolic Disease Inflammation/Immunology

TXNIP-IN-1 is TXNIP-TRX (thioredoxin-interacting protein- thioredoxin) complex inhibitor extracted from patent US20200085800A1, Compound 1. TXNIP-IN-1 can be used in the research of TXNIP-TRX complex associated metabolic disorder (diabetes), cardiovascular disease, or inflammatory disease .
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2
Curdione
Curdione
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2 Cited Publications
Cat. No.: HY-N0353
CAS No.: 13657-68-6
Synonyms: (+)-Curdione
Category:  

Zingiberaceae Extract Terpenoids Sesquiterpenes Other Diseases Plants 500 - Internal Server Error | MedChemExpress

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