country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

80 Results for "

TXA

" in MedChemExpress (MCE) Product Catalog:

Products (80)

Sort by :

Categories

By Targets

Hosts:

Reactivities:

Applications:

Isotypes:

Conjugations:

Clonalities:

Modifications:

Products

Talfirastide

19 Publications Verification

Cat. No.: HY-12403

CAS No.: 51833-78-4

Purity: 99.75%

Synonyms: TXA127; Angiotensin (1-7); Ang-(1-7)

Category:

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Angiotensin Receptor Angiotensin-converting Enzyme (ACE)

Angiotensin 1-7 (Ang-(1-7)) is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium. Angiotensin 1-7 shows anti-inflammatory activity .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Talfirastide acetate

19 Publications Verification

Cat. No.: HY-12403A

CAS No.: 2855063-75-9

Purity: 99.87%

Synonyms: TXA127 acetate; Angiotensin (1-7) acetate; Ang-(1-7) acetate

Category:

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology Endocrinology

Target:

Angiotensin Receptor Angiotensin-converting Enzyme (ACE) Endogenous Metabolite

Angiotensin 1-7 (Ang-(1-7)) acetate is an endogenous heptapeptide from the renin-angiotensin system (RAS) with a cardioprotective role due to its anti-inflammatory and anti-fibrotic activities in cardiac cells. Angiotensin 1-7 acetate inhibits purified canine ACE activity (IC₅₀=0.65 μM). Angiotensin 1-7 acetate acts as a local synergistic modulator of kinin-induced vasodilation by inhibiting ACE and releasing nitric oxide. Angiotensin 1-7 acetate blocks Ang II-induced smooth muscle cell proliferation and hypertrophy and shows antiangiogenic and growth-inhibitory effects on the endothelium .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

U-46619

18 Cited Publications

Cat. No.: HY-108566

CAS No.: 56985-40-1

Purity: ≥98.0%

Synonyms: 9,11-Methanoepoxy PGH2

Target:

Prostaglandin Receptor

Research Areas:

Cardiovascular Disease

U-46619 (9,11-Methanoepoxy PGH2) is a stable analogue of Thromboxane A2 (HY-113350) (TXA2) and acts as a potent TXA2 (TP) agonist. U-46619 also is a RhoA agonist. U-46619 stimulates the activation of RhoA through TXA2 receptor activation .

Compare

Please select quantity

August 31

Get Quote

View All Sizes

Indobufen

3 Cited Publications

Cat. No.: HY-18763

CAS No.: 63610-08-2

Synonyms: Ibustrin

Target:

COX

Research Areas:

Cardiovascular Disease

Indobufen is a platelet aggregation inhibitor. Indobufen is a reversible platelet cyclooxygenase (Cox) activity inhibitor. Indobufen suppresses thromboxane A₂ (TxA₂) synthesis. Indobufen down-regulates tissue factor (TF) in monocytes .

Compare