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28 Results for "

Tcf/4

" in MedChemExpress (MCE) Product Catalog:

Products (28)

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LF3

14 Publications Verification

Cat. No.: HY-101486

CAS No.: 664969-54-4

Purity: 99.55%

Target:

β-catenin

Research Areas:

Cancer

LF3 is an antagonist of the β-Catenin/TCF4 interaction with antitumor activity; has an IC₅₀ of 1.65 μM .

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Toxoflavin

9 Cited Publications

Cat. No.: HY-100760

CAS No.: 84-82-2

Purity: 99.88%

Synonyms: Xanthothricin; Toxoflavine; PKF-118-310

Target:

β-catenin Bacterial Antibiotic Histone Demethylase

Research Areas:

Infection Cancer

Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex, also acts as an inhibitor of KDM4A, with antitumor and antibiotic activity .

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Chlorquinaldol

6 Cited Publications

Cat. No.: HY-B1360

CAS No.: 72-80-0

Synonyms: Chloquinan

Target:

Antibiotic Bacterial Fungal β-catenin Apoptosis

Research Areas:

Infection Cancer

Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells .

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TCF-4/TCF7L2 Antibody (YA039)

1 Cited Publications

Cat. No.: HY-P80520

Synonyms: Tcf4, Tcf7L2, Transcription factor 7-like 2, HMG box transcription factor 4, T-cell-specific transcription factor 4, T-cell factor 4, Tcf-4, hTcf-4

Host:

Rabbit

Application:

WB, ICC/IF, IHC-P, IP, FC

Reactivity:

Human, Mouse

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HB007

Cat. No.: HY-139662

CAS No.: 2387821-46-5

Purity: 99.73%

Target:

Molecular Glues E1/E2/E3 Enzyme

Research Areas:

Cancer

HB007 is a SUMO1 molecular glue degrader targeting CAPRIN1 and FBXO42. HB007 selectively binds CAPRIN1 to induce CAPRIN1-FBXO42 interaction, recruits SUMO1 to the CAPRIN1-CUL1-FBXO42 E3 ligase complex, and drives SUMO1 ubiquitination and degradation without affecting SUMO2/3. HB007 induces TCF4 deSUMOylation and proteasomal degradation to inhibit StarD7 transcriptional activity, reduces StarD7 mRNA and protein levels, and triggers ER stress and ROS production. HB007 can be used for the research of brain cancer, breast cancer, colon cancer, lung cancer .

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UU-T01

Cat. No.: HY-122649

CAS No.: 1417162-83-4

Purity: 96.92%

Target:

β-catenin

Research Areas:

Cancer

UU-T01 is a β-catenin inhibitor with a K_D of 0.531 μM. UU-T01 binds to the K435, R469 and K508 residues of β-catenin, disrupting the β-catenin/TCF4 protein-protein interaction .

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