10 Results for "

Tetrandrine

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "Tetrandrine" in MCE Product Catalog:

20
20 Cited Publications
Cat. No.: HY-13764
CAS No.: 518-34-3
Purity:  99.90%
Synonyms: NSC-77037; d-Tetrandrine
Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca 2+ current (ICa) and Ca 2+-activated K + current.
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Cat. No.: HY-13764R
CAS No.: 518-34-3
Synonyms: NSC-77037 (Standard); d-Tetrandrine (Standard)
Tetrandrine (Standard) is the analytical standard of Tetrandrine. This product is intended for research and analytical applications. Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current.
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Cat. No.: HY-13764A
CAS No.: 23495-89-8
dl-Tetrandrine is an orally active and brain-penetrant calcium channel blocker that inhibits voltage-dependent calcium channels. dl-Tetrandrine selectively blocks Ca 2+ influx with an IC50 value of approximately 1-10 μM. dl-Tetrandrine exerts anti-inflammatory, immunosuppressive, and anti-arrhythmic activities by inhibiting intracellular calcium overload, and can reverse multidrug resistance in tumor cells. dl-Tetrandrine is promising for research of autoimmune diseases (such as rheumatoid arthritis), cardiovascular diseases, and tumor drug resistance reversal .
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Cat. No.: HY-146096
CAS No.: 2497686-66-3
Research Areas:  

Cancer

RMS3, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS3 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS3 has strong anticancer property .
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Cat. No.: HY-105515
CAS No.: 118160-59-1
Target:  

Others

Research Areas:  

Cardiovascular Disease

TJN 220 is a synthetic derivative of orally active tetrandrine (HY-13764). TJN 220 has a long-lasting and stable antihypertensive effect in various hypertension models. TJN 220 is suitable for controlling nighttime hypertension and does not cause reflex tachycardia. TJN 220 can be used for research on hypertension .
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Cat. No.: HY-149053
CAS No.: 41183-02-2
Target:  

P-glycoprotein

Research Areas:  

Cancer

OY-101 is an orally active, potent and specific P-glycoprotein (P-gp) inhibitor. OY-101 can sensitize drug-resistant tumors and effectively reverse tumor multidrug resistance. OY-101 is improvements in water-solubility, cytotoxicity, and reversal activity compared to Tetrandrine (HY-13764) .
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Cat. No.: HY-121247
CAS No.: 62067-29-2
Synonyms: 5-BromoTetrandrine; BrTet; W198
Research Areas:  

Cancer

Bromotetrandrine is a potent inhibitor of P-glycoprotein (P-gp)-mediated multidrug resistance (MDR). Bromotetrandrine shows significant MDR reversal activity in vitro and in vivo, which may be related to the inhibition of P-gp overexpression and the increase in intracellular accumulation of anticancer agents. Bromotetrandrine is a brominated derivative of tetrandrine, which is promising for MDR modulator for tumor assessment .
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Cat. No.: HY-146097
CAS No.: 2497686-68-5
Research Areas:  

Cancer

RMS5, a tetrandrine analogue, is a potent P-glycoprotein (P-gp) inhibitor. RMS5 has markedly antiproliferative and cytotoxic effects on cancer cells. RMS5 slightly diminishes the expression of the anti-apoptotic Bcl-2 family proteins Bcl-XL and Mcl-1. RMS3 causes PARP cleavage, a marker for cells undergoing apoptosis. RMS5 has strong anticancer property .
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Cat. No.: HY-N17761A
CAS No.: 62828-25-5
Tetrandrine 2'-N-β-oxide is an anti-hyperglycemic dibenzylisoquinoline alkaloid. At a dose of 1 mg/kg, Tetrandrine 2'-N-β-oxide can reduce hyperglycemia levels in streptozotocin (HY-13753)-induced diabetic mice to nearly 50% of their original levels. Tetrandrine 2'-N-β-oxide is primarily used in research related to the anti-hyperglycemic of type 2 diabetes.
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Cat. No.: HY-N17761
CAS No.: 90365-80-3
Tetrandrine 2'-N-α-oxide (compound 13) is a bisbenzylisoquinoline alkaloid anti-inflammatory agent that can be isolated from the roots of Stephania tetrandra. Tetrandrine 2'-N-α-oxide may be used in research related to inflammatory diseases.
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