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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
Tha
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "Tha" in MCE Product Catalog:
8
8 Cited Publications
Cat. No.: HY-B2244
CAS No.: 206658-92-6
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Tacrine hydrochloride (hydrate) is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.
Cat. No.: HY-W1008621
CAS No.: 2058062-52-3
Cat. No.: HY-CE00356
Synonyms: 3-keto-Tha-Coenzyme A
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(6Z,9Z,12Z,15Z,18Z,21Z)-3-Oxotetracosahexaenoyl-CoA (3-keto-THA-Coenzyme A) is an unsaturated fatty acyl-CoA.
Cat. No.: HY-CE00482
Synonyms: 1-3-Hydroxy-Tha-coenzyme A
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1-(3-Hydroxy-6Z,9Z,12Z,15Z,18Z,21Z-tetracosahexaenoyl)-CoA (1-3-Hydroxy-THA-coenzyme A) is a coenzyme A derivative.
Cat. No.: HY-P10068A
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Cat. No.: HY-15116
CAS No.: 117427-00-6
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ONO 1603, a novel prolyl endopeptidase inhibitor investigated as a potential antidementia drug, demonstrated neuroprotective and neurotrophic effects in cerebellar granule cells similar to tetrahydroaminoacridine (THA). At a concentration of 0.03 microM, ONO 1603 promoted neuronal survival, enhanced neurite outgrowth, increased m3-muscarinic acetylcholine receptor (mAChR) mRNA levels, and stimulated mAChR-mediated signaling pathways. These findings suggest that ONO 1603 shares pharmacological similarities with THA, indicating its potential as a therapeutic agent for Alzheimer's disease by enhancing cholinergic neurotransmission and neuronal function .
Cat. No.: HY-CE00239A
Synonyms: Delta2-Tha-coenzyme A
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(2E,6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosaheptaenoyl-CoA (Delta2-THA-coenzyme A) is an unsaturated fatty acyl-CoA.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
