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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
46 Results for "
Theophylline
" in MedChemExpress (MCE) Product Catalog:
Products (46)
46 Results for "Theophylline" in MCE Product Catalog:
15
15 Publications Verification
Synonyms: 1,3-Dimethylxanthine; Theo-24
12
12 Cited Publications
Synonyms: 1,3-Dimethylxanthine monohydrate; Theo-24 monohydrate
6
Category:
Target:
1
1 Cited Publications
Synonyms: Theophyllineacetic acid; Theophylline-7-acetic acid
1
Target:
Research Areas:
Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline .
Target:
Research Areas:
Etofylline (7-(β-Hydroxyethyl) theophylline) is an oral bronchodilator with anti-inflammatory effects. Etofylline inhibits phosphodiesterase and prevents the degradation of cAMP (cyclic adenosine monophosphate), leading to smooth muscle relaxation, reducing inflammatory responses and improving respiratory function. Etofylline affects the development of zebrafish embryos .
Cat. No.: HY-W008449
CAS No.: 6136-37-4
Category:
Human Gut Microbiota Metabolites Natural Products Endogenous metabolite Disease Research Fields Cancer
Target:
Cat. No.: HY-B0809S
CAS No.: 117490-39-8
Synonyms: 1,3-Dimethylxanthine-d6; Theo-24-d6
Cat. No.: HY-W014993
CAS No.: 944-73-0
Target:
Cat. No.: HY-B1505A
CAS No.: 18833-13-1
Synonyms: Theophyllineacetic acid piperazine; Theophylline-7-acetic acid piperazine
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology
Acefylline (Theophyllineacetic acid) piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research .
Category:
Alkaloids Plant Nelumbo nucifera Gaertn. Extract Metabolic Disease Phenols Polyphenols Nymphaeaceae Extract Disease Research Fields Isoquinoline Alkaloids
Target:
Cat. No.: HY-101036R
CAS No.: 87-67-2
Category:
Synonyms: 1,3-Dimethylxanthine (sodium glycinate); Theo-24 (sodium glycinate)
Research Areas:
Theophylline (1,3-Dimethylxanthine) sodium glycinate is a potent phosphodiesterase (PDE) inhibitor, adenosine receptor antagonist, and histone deacetylase (HDAC) activator. Theophylline sodium glycinate inhibits PDE3 activity to relax airway smooth muscle. Theophylline sodium glycinate has anti-inflammatory activity by increase IL-10 and inhibit NF-κB into the nucleus. Theophylline sodium glycinate induces apoptosis. Theophylline sodium glycinate can be used for asthma and chronic obstructive pulmonary disease (COPD) research .
Cat. No.: HY-18768A
CAS No.: 2080306-22-3
Target:
Research Areas:
NCT-501 hydrochloride is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC50 of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC50 >57 μM) .
Cat. No.: HY-175257
Target:
PARP Reactive Oxygen Species (ROS) Apoptosis NF-κB ERK Bcl-2 Family TGF-β Receptor EGFR Cadherin
Research Areas:
Theophylline-platinum(IV) prodrug-1 is a PARP-1 inhibitor. Theophylline-platinum(IV) prodrug-1 enhances DNA
damage, ROS production, mitochondrial dysfunction, apoptosis and S-phase arrest, along with reducing invasion and metastasis in cells. Theophylline-platinum(IV) prodrug-1 exhibits superior antitumor activity in the xenograft SKOV3-BRCA1-KD tumor model. Theophylline-platinum(IV) prodrug-1 can be used for the study of ovarian cancer .
Cat. No.: HY-W173257
CAS No.: 7597-60-6
Synonyms: 6-Amino-5-1,3-dimethyl-5-(formamido)uracil
Target:
Theophylline EP impurity C is an alkaloid with anti-bronchial smooth muscle spasm activity. Theophylline EP impurity C can be used to assess the purity and quality of compounds. Theophylline EP impurity C has potential clinical value in the suppression of asthma and chronic obstructive pulmonary disease.
Cat. No.: HY-129092
CAS No.: 80206-91-3
Synonyms: 8-SPT; 8-pSPT
Target:
Research Areas:
8-(p-Sulfophenyl)theophylline (8-SPT) (compound 2) is an adenosine A2B receptor antagonist, with a Ki of 1330 nM for A2B human recombinant .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
