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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
1 Result for "
Tibremciclib
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "Tibremciclib" in MCE Product Catalog:
Cat. No.: HY-156646
CAS No.: 2397678-18-9
Synonyms: BPI-16350
Tibremciclib (BPI-16350) is an orally active CDK4/6 inhibitor. Tibremciclib selectively inhibits CDK4/cyclin D1 and CDK6/cyclin D1 with IC50 values of 2.21 nM and 0.407 nM, respectively. Tibremciclib blocks Rb phosphorylation and cell cycle progression, and induces G1 phase arrest in Rb-positive tumor cells, exhibiting broad-spectrum anti-tumor cell proliferation activity. Tibremciclib inhibits MATE1 and MATE2-K. Tibremciclib dose-dependently inhibits tumor growth in xenograft models, and shows synergistic effects when combined with Fulvestrant (HY-13636). Tibremciclib can be used for research related to breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
