1 Result for "

ToxT

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ToxT" in MCE Product Catalog:

Cat. No.: HY-127041
CAS No.: 88909-96-0
Purity:  98.00%
Target:  

Bacterial COX NO Synthase

Research Areas:  

Infection

Virstatin is an orally effective Vibrio cholerae virulence inhibitor. Virstatin blocks the expression of downstream virulence genes, such as cholera toxin (ctx) and toxin-coregulated pilus (tcpA), at the post-transcriptional level by inhibiting the dimerization of the transcriptional activator ToxT. Virstatin inhibits Vibrio cholerae-induced expression of COX-2 and iNOS, and exerts bactericidal effects at high concentrations. Virstatin can be used for research on cholera .
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