446 Results for "

Transmembrane Glycoprotein

" in MedChemExpress (MCE) Product Catalog:
Products (446)

446 Results for "Transmembrane Glycoprotein" in MCE Product Catalog:

29
29 Publications Verification
Cat. No.: HY-15206
CAS No.: 10238-21-8
Purity:  99.94%
Synonyms: Glyburide
Glibenclamide (Glyburide) is an orally active ATP-sensitive K + channel (KATP) inhibitor and can be used for the research of diabetes and obesity . Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR) . Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability . Glibenclamide can induce autophagy .
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6
6 Cited Publications
Cat. No.: HY-P0168
CAS No.: 1208243-50-8
Synonyms: ARA290
Research Areas:  

Neurological Disease

Cibinetide (ARA290) is an erythropoietin (EPO) derivative that acts as a specific agonist of the erythropoietin/CD131 heteroreceptor. ICibinetide can be used in the research of neurological disorders .
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4
4 Cited Publications
Cat. No.: HY-P99129

Research Areas:  

Inflammation/Immunology

Anti-Mouse CD8a Antibody (53-6.7) is an anti-mouse CD8a IgG2a antibody inhibitor derived from host Rat. Anti-Mouse CD8a Antibody (53-6.7) binds to CD8αβ stabilizes a conformation with a higher affinity for interaction with MHC class I. Anti-Mouse CD8a Antibody (53-6.7) induces the phosphorylation and activation of TCR proximal signaling pathway components Lck and ZAP70 in polyclonal memory T cells. Anti-Mouse CD8a Antibody (53-6.7) depletes CD8+ T cells and neutralizes cytokine in mice .
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4
4 Cited Publications
Cat. No.: HY-P99126
Anti-Mouse/Human CD44 Antibody (IM7) is an anti-huamn and mouse CD44 IgG2b monoclonal antibody that recognizes a conserved epitope outside the HA-binding domain of the CD44 molecule. Anti-Mouse/Human CD44 Antibody (IM7) exerts a potent anti-inflammatory effect by inducing the shedding of cell surface CD44, significantly improving symptoms in mice with rheumatoid arthritis without affecting relevant immune responses. Anti-Mouse/Human CD44 Antibody (IM7) can be used for researches on inflammation conditions and cancer such as arthritis and osteosarcoma .
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4
4 Cited Publications
Cat. No.: HY-102022
CAS No.: 158021-47-7
Purity:  95.59%
Synonyms: α-GalCer; KRN7000
α-Galactosylceramide (α-GalCer) is a synthetic glycolipid with antitumorial and immunostimulatory. α-Galactosylceramide is a very potent NKT cell agonist and binds effectively to CD1d. The complex of α-Galactosylceramide plus CD1d binds the NKT cell TCR (T cell antigen receptor) .
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4
4 Cited Publications
Cat. No.: HY-157122
CAS No.: 2765319-65-9
Purity:  99.68%
VJDT is a TREM1 inhibitor that can effectively block TREM1 signaling. VJDT inhibits tumor cell proliferation and migration and induces cell cycle arrest. VJDT has immunomodulatory and antitumor activities, and can be used for the research of tumors such as melanoma .
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3
3 Cited Publications
Cat. No.: HY-P75951
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPNMB; Glycoprotein Nonmetastatic Melanoma Protein B; Glycoprotein Nmb; Osteoactivin; HGFIN; Hematopoietic Growth Factor Inducible Neurokinin-1; NMB; Transmembrane Glycoprotein HGFIN; Glycoprotein (Transmembrane) Nmb; Uncharacterized Protein GPNMB; Transm
Species:  
Human
Source:  
HEK293
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3
3 Cited Publications
Cat. No.: HY-P99208
CAS No.: 1000676-41-4
Synonyms: IPH2102

Research Areas:  

Cancer

Lirilumab (IPH2102) is an anti-KIR monoclonal antibody, and shows antitumor activity. Lirilumab can be used in Leukemia, squamous cell carcinoma of the head and neck (SCCHN) research .
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3
3 Cited Publications
Cat. No.: HY-149897
CAS No.: 3009761-01-4
Purity:  99.36%
Research Areas:  

Cancer

HA-CD44 interaction inhibitor 2 is a CD44 inhibitor that can inhibit the interaction between Hyaluronic acid (HA) (HY-B0633A) and CD44. HA-CD44 interaction inhibitor 2 acts as an antiproliferative agent against CD44 + cancer cells. HA-CD44 interaction inhibitor 2 can disrupt the integrity of cancer spheres and reduce cancer cell viability in a dose-dependent manner. HA-CD44 interaction inhibitor 2 is applicable for tumor research .
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3
3 Cited Publications
Cat. No.: HY-P99042
CAS No.: 2279068-37-8
Polatuzumab is a monoclonal antibody that targets CD79b on the surface of B cells. Polatuzumab can be used to synthesize the ADC Polatuzumab Vedotin (HY-132253), which has anti-tumor activity .
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2
2 Cited Publications
Cat. No.: HY-P2284
CAS No.: 959961-23-0
Research Areas:  

Cancer

AD 01, a 24 amino acid peptide of FKBPL (FK506-binding protein like), possesses potent anti-angiogenic activity. AD 01 bind to the CD44 receptor and inhibit tumour cell migration in a CD44 dependant manner .
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2
2 Cited Publications
Cat. No.: HY-P1242
CAS No.: 475221-20-6
Research Areas:  

Inflammation/Immunology

NEP(1-40) is a Nogo-66 receptor (NgR) antagonist peptide, reversing the injury-induced shift in distribution of microglia morphologies by limiting myelin-based inhibition .
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2
2 Cited Publications
Cat. No.: HY-P77116
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GPNMB; Glycoprotein Nonmetastatic Melanoma Protein B; Glycoprotein Nmb; Osteoactivin; HGFIN; Hematopoietic Growth Factor Inducible Neurokinin-1; NMB; Transmembrane Glycoprotein HGFIN; Glycoprotein (Transmembrane) Nmb; Uncharacterized Protein GPNMB; Transmembrane Glycoprotein NMB; Transmembrane Glycoprotein; Glycoprotein Nmb-Like Protein; GPNMB Protein; Hematopoietic Growth Factor Inducible Neurokinin-1 Type; PLCA3
Species:  
Mouse
Source:  
HEK293
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2
2 Cited Publications
Cat. No.: HY-P99051
CAS No.: 2226224-30-0
Synonyms: BAY 1834942
Tinurilimab (Bay 1834942) is an anti-CEACAM6 (carcinoembryonic antigen-related cell adhesion molecule 6) humanized IgG2 monoclonal antibody. CEACAM6 is an immune checkpoint regulator suppressing the activity of effector T-cells against tumors. Tinurilimab shows an increased tumor cell killing effect in the tumor-cell/T-cell co-culture system .
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2
2 Cited Publications
Cat. No.: HY-P990859

Research Areas:  

Cancer

Anti-CD44 Antibody (Hermes-1) is a kind of rat IgG2a κ chimeric antibody, targeting to human CD44. Anti-CD44 Antibody (Hermes-1) blocks the binding of hyaluronan to CD44. Anti-CD44 Antibody (Hermes-1) restores (Platelet-derived Growth Factor-BB)-induced β-receptor activation and motility in fibroblasts. Anti-CD44 Antibody (Hermes-1) causes partial loss of the anti-aging effect of hyaluronic .
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2
2 Cited Publications
Cat. No.: HY-P99227
CAS No.: 915810-67-2
Synonyms: ALX-0681; ALX-0081
Caplacizumab (His Tag) is a humanized anti-von Willebrand factor (vWF) nanobody. Caplacizumab (His Tag) inhibits the binding of vWF with platelet glycoprotein (GP) Ibα. Caplacizumab (His Tag) inhibits the vWF-mediated platelet adhesion and prevents further microthrombi formation. Caplacizumab (His Tag) can be used for the research of thrombotic thrombocytopenic purpura (TTP) .
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1
1 Cited Publications
Cat. No.: HY-153084A
Target:  

mRNA CD19

Research Areas:  

Cancer

CD19 CAR mRNA (Human) expresses CAR protein that specifically targets human CD19. CD19 CAR mRNA can trigger transitory expression of CAR, allowing T cells to be targeted without permanent genetic modification. CD19 CAR mRNA targets CD19 which is a transmembrane glycoprotein primarily expressed on B lymphocytes and is important in B cell activation. CD19 CAR mRNA can be studied in cancer research such as lymphoma and leukemia .
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1
1 Cited Publications
Cat. No.: HY-15206S
CAS No.: 1189985-02-1
Glyburide-d11 is the deuterium labeled Glibenclamide. Glibenclamide (Glyburide) is an orally active ATP-sensitive K+ channel (KATP) inhibitor and can be used for the research of diabetes and obesity . Glibenclamide inhibits P-glycoprotein. Glibenclamide directly binds and blocks the SUR1 subunits of KATP and inhibits the cystic fibrosis transmembrane conductance regulator protein (CFTR) . Glibenclamide interferes with mitochondrial bioenergetics by inducing changes on membrane ion permeability . Glibenclamide can induce autophagy .
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1
1 Cited Publications
Cat. No.: HY-P70907
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Envelope Glycoprotein gp160; Env polyprotein; Surface protein gp120; SU; Glycoprotein 120; gp120; Transmembrane protein gp41; TM; Glycoprotein 41; gp41 ; env
Species:  
Virus
Source:  
HEK293
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1
1 Cited Publications
Cat. No.: HY-P990572

Research Areas:  

Inflammation/Immunology

DCBY02 is a monoclonal antibody targeting CD93 expressed in CHO cells. DCBY02 has a heavy chain of the mlgG type and a light chain of the mkappa type, with a predicted molecular weight (MW) of 150 kDa. The isotype control for DCBY02 can be referenced as Mouse IgG1 kappa, Isotype Control.
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