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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
Trp104
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "Trp104" in MCE Product Catalog:
2
Target:
Research Areas:
Sirpiglenastat (DRP-104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and simultaneously inducing a potent antitumor immune response .
Cat. No.: HY-121029
CAS No.: 862501-61-9
Synonyms: KRP-104
Target:
Research Areas:
Bisegliptin (KRP-104) is a small molecule compound with antidiabetic activity. Bisegliptin is metabolized mainly by converting the cyano group to the carboxylic acid form, and DPP-4 plays a partial role in its metabolism. The carboxylic acid metabolite of bisegliptin can be detected both in vivo and in vitro. In rat experiments, the plasma concentration of the carboxylic acid metabolite of bisegliptin was affected by other DPP inhibitors, showing the complexity of its metabolic process. The amide intermediate of bisegliptin was detected both in vivo and in vitro, and its conversion rate was significantly faster than that of the parent compound when incubated with DPP-4 .
Cat. No.: HY-P811968
Synonyms: TXNL5, TXNDC17, Thioredoxin domain-containing protein 17, 14 kDa thioredoxin-related protein, Protein 42-9-9, Thioredoxin-like protein 5, Trp14
Cat. No.: HY-P811968A
Synonyms: TXNL5, TXNDC17, Thioredoxin domain-containing protein 17, 14 kDa thioredoxin-related protein, Protein 42-9-9, Thioredoxin-like protein 5, Trp14
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
