Category:

Cardiovascular Disease Human Gut Microbiota Metabolites Microorganisms Monophenols Disease markers Phenols Nervous System Disorder Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

Tyramine is an amino acid that helps regulate blood pressure. Tyramine occurs naturally in the body, and it's found in certain foods .

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8

Clorgyline hydrochloride

8 Publications Verification

Cat. No.: HY-14197A

CAS No.: 17780-75-5

Purity: 99.92%

Synonyms: M&B 9302 hydrochloride

Target:

Monoamine Oxidase 5-HT Receptor Bcl-2 Family

Clorgyline hydrochloride (M&B 9302 hydrochloride) is a selective, irreversible monoamine oxidase A (MAO-A) inhibitor that can cross the blood-brain barrier and exhibits activity against the 5-HT Receptor at very high doses. Clorgyline hydrochloride regulates monoamine neurotransmitter levels, the release of dopamine and acetylcholine, the uptake and effects of Tyramine (HY-W007606), noradrenergic function, circadian locomotor activity rhythms, feeding behavior, and body weight. Clorgyline hydrochloride induces tumor-suppressive transcriptional programs, secretory differentiation, androgen signaling regulation, Bcl-2 expression, and radioprotective effects in non-malignant cells. Clorgyline hydrochloride is used in the research of high-grade prostate cancer, Huntington's disease, major affective disorder, radiation-induced normal tissue toxicity, and obesity .

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8

Clorgyline

8 Publications Verification

Cat. No.: HY-14197

CAS No.: 17780-72-2

Purity: 99.76%

Synonyms: M&B 9302

Target:

Monoamine Oxidase 5-HT Receptor Bcl-2 Family

Research Areas:

Neurological Disease Metabolic Disease Cancer

Clorgyline (M&B 9302) is a selective, irreversible monoamine oxidase A (MAO-A) inhibitor that can cross the blood-brain barrier and exhibits activity against the 5-HT Receptor at very high doses. Clorgyline regulates monoamine neurotransmitter levels, the release of dopamine and acetylcholine, the uptake and effects of Tyramine (HY-W007606), noradrenergic function, circadian locomotor activity rhythms, feeding behavior, and body weight. Clorgyline induces tumor-suppressive transcriptional programs, secretory differentiation, androgen signaling regulation, Bcl-2 expression, and radioprotective effects in non-malignant cells. Clorgyline is used in the research of high-grade prostate cancer, Huntington's disease, major affective disorder, radiation-induced normal tissue toxicity, and obesity .

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1

Alrestatin

1 Cited Publications

Cat. No.: HY-B1202

CAS No.: 51411-04-2

Synonyms: AY-22284

Target:

Aldose Reductase

Research Areas:

Metabolic Disease

Alrestatin (AY-22284) is an aldose reductase inhibitor. Alrestatin reduces fructose levels in the uterine fluid of mice. Alrestatin interferes with sperm capacitation and impairs fertilization function in mice. Alrestatin decreases basal and tyramine-induced norepinephrine release in rat pancreatic specimens in vitro. Alrestatin enhances glucose- and arginine-stimulated insulin secretion in vivo. Alrestatin can be used in studies related to diabetes and reproductive diseases .

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Tyramine hydrochloride

Cat. No.: HY-W016823

CAS No.: 60-19-5

Category:

Cardiovascular Disease Monophenols Phenols Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods .

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p-Tyramine-d4 hydrochloride

Cat. No.: HY-W016823S

CAS No.: 1189884-47-6

p-Tyramine-d₄ (hydrochloride) is the deuterium labeled Tyramine hydrochloride. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods .

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Tyramine O-sulfate

Cat. No.: HY-156836

CAS No.: 30223-92-8

Synonyms: Tyramine sulfate

Target:

Drug Metabolite

Research Areas:

Neurological Disease

Tyramine O-sulfate (Tyramine sulfate) is a metabolite of Tyramine (HY-W007606) formed via sulfation, which serves as a biomarker for depression. Tyramine O-sulfate can be used in the research of depression .

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m-Tyramine hydrobromide

Cat. No.: HY-128975

CAS No.: 38449-59-1

Purity: 98.50%

Category:

Alkaloids Monophenols Neurological Disease Other Alkaloids Phenols Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

m-Tyramine hydrobromide is an endogenous trace amine neuromodulator. m-Tyramine hydrobromide has effects on the adrenergic and dopaminergic receptor ^{[1, 2]}.

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Tyramine oxidase, Microorganism

Cat. No.: HY-E70519

CAS No.: 37255-42-8

Target:

Monoamine Oxidase

Research Areas:

Cardiovascular Disease Neurological Disease

Tyramine oxidase, Microorganism (EC 1.4.3.4) is a copper enzyme found in the cytoplasm of animal cells that catalyzes the oxidation of phenolic amine substrates. Tyramine oxidase, Microorganism involves in the metabolism and clearance of phenolamine compounds and has an important role in maintaining homeostasis in vivo. Tyramine oxidase, Microorganism is promising for research of hypertension, asthma, and depression .

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4-Hydroxybenzyl cyanide

Cat. No.: HY-W015823

CAS No.: 14191-95-8

Category:

Monophenols Metabolic Disease Phenols Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

4-Hydroxybenzyl cyanide is an aromatic nitrile compound and also a precursor for tyramine synthesis. 4-Hydroxybenzyl cyanide exhibits strong antioxidant activity .

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Tyramine (Standard)

Cat. No.: HY-W007606R

CAS No.: 51-67-2

Category:

Human Gut Microbiota Metabolites Microorganisms Monophenols Disease markers Phenols Nervous System Disorder Endogenous metabolite

Target:

Reference Standards Endogenous Metabolite

Tyramine (Standard) is the analytical standard of Tyramine. This product is intended for research and analytical applications. Tyramine is an amino acid that helps regulate blood pressure. Tyramine occurs naturally in the body, and it's found in certain foods .

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Amezinium methylsulfate

Cat. No.: HY-A0275

CAS No.: 30578-37-1

Synonyms: Amezinium metilsulfate; Lu-1631

Target:

Adrenergic Receptor

Research Areas:

Cardiovascular Disease Endocrinology

Amezinium metilsulfate has multiple mechanisms, including stimulation of alpha and beta-1 receptors and inhibition ofnoradrenaline and tyramine uptake.

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Tyramine O-sulfate sodium

Cat. No.: HY-156836A

CAS No.: 2083619-07-0

Synonyms: Tyramine sulfate sodium

Target:

Drug Metabolite

Research Areas:

Neurological Disease

Tyramine O-sulfate (Tyramine sulfate) sodium is a metabolite of Tyramine (HY-W007606) formed via sulfation, which serves as a biomarker for depression. Tyramine O-sulfate sodium can be used in the research of depression .

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Tyramine hydrochloride (Standard)

Cat. No.: HY-W016823R

CAS No.: 60-19-5

Category:

Monophenols Phenols Endogenous metabolite

Target:

Reference Standards Endogenous Metabolite

Tyramine (hydrochloride) (Standard) is the analytical standard of Tyramine (hydrochloride). This product is intended for research and analytical applications. Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods .

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Tyrosine decarboxylase, Microorganism

Cat. No.: HY-P2825

CAS No.: 9002-09-9

Synonyms: TDC; TyrDC

Target:

Endogenous Metabolite

Research Areas:

Others

Tyrosine decarboxylase, Microorganism (TDC) is a tyrosine decarboxylase produced by microorganisms. Tyrosine decarboxylase is a PLP-dependent enzyme that catalyzes the decarboxylation of L-tyrosine, L-phenylalanine, and L-dopa to produce tyramine, 2-phenethylamine, and dopamine, respectively. Tyrosine decarboxylase mediates acid stress resistance, maintains intracellular pH homeostasis, and generates proton motive force .

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Tyramine-d4 hydrochloride

Cat. No.: HY-W744225

CAS No.: 1188266-06-9

Tyramine-d₄ hydrochloride is the deuterium labeled Tyramine hydrochloride (HY-W016823). Tyramine hydrochloride is an amino acid that helps regulate blood pressure. Tyramine hydrochloride occurs naturally in the body, and it's found in certain foods .

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Diclofensine

Cat. No.: HY-18610A

CAS No.: 67165-56-4

Synonyms: Ro 8-4650

Target:

Dopamine Transporter Adrenergic Receptor 5-HT Receptor

Research Areas:

Neurological Disease

Diclofensine (Ro 8-46500) is an orally active neuronal monoamine uptake inhibitor. Diclofensine blocks the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC₅₀ values of 0.74, 2.3 and 3.7 nM, respectively. Diclofensine potentiates norepinephrine-induced hypertension and attenuates Tyramine (HY-W007606)-induced hypertension. Diclofensine produces psychostimulant and mood-elevating effects without causing sudden disappearance or withdrawal reactions. Diclofensine can be used in the research of moderate to severe depression .

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