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19 Results for "

U-251

" in MedChemExpress (MCE) Product Catalog:

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AMZ30

1 Cited Publications

Cat. No.: HY-12833

CAS No.: 1313613-09-0

Purity: 99.76%

Target:

Phosphatase Akt ERK

Research Areas:

Others

AMZ30 is selective protein phosphatase methylesterase-1(PME-1) inhibitor with IC₅₀s of 600 nM and 3.5 µM in human cell lysates and in HEK 293T cells, respectively. AMZ30 shows >100-fold selectivity relative to other serine hydrolases. AMZ30 reduces the demethylated form of PP2A in living cells. AMZ30 attenuates muscle cell differentiation. AMZ30 increases the resistance of U87MG and U251MG glioblastoma cells to t-BHP-induced oxidative stress. AMZ30can be used for the study of glioblastoma .

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August 31

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Topotecan-d6

Cat. No.: HY-13768S1

CAS No.: 1044904-10-0

Topotecan-d₆ is the deuterium labeled Topotecan. Topotecan (SKF 104864A; NSC 609669) is a Topoisomerase I inhibitor. The IC₅₀ values of Topotecan at 24 h are 2.73±0.25 μM of U251 cells, 2.95±0.23 μM of U87 cells, 5.46±0.41 μM of GSCs-U251 and 5.95 μM of GSCs-U87 .

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