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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
UGT1ab
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "UGT1ab" in MCE Product Catalog:
Synonyms: UGT1A4
Target:
Research Areas:
Trifluoperazine N-Glucuronide (UGT1A4), as one of the human UGT1A isoforms, is expressed in the liver. Trifluoperazine N-Glucuronide catalyzes the imipramine and trifluoperazine Nglucuronide formation .
Cat. No.: HY-N13388
CAS No.: 27939-38-4
Synonyms: UGT1A6
Target:
Cat. No.: HY-137083A
CAS No.: 145850-78-8
Synonyms: UGT1A4 chloride
Target:
Research Areas:
Trifluoperazine N-glucuronide (UGT1A4) chloride is a metabolite of the antipsychotic agent trifluoperazine. Trifluoperazine N-glucuronide (UGT1A4) chloridecatalyzes the imipramine and trifluoperazine Nglucuronide formation .
Cat. No.: HY-RS15426
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UGT1A1 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15428
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UGT1A3 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15429
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UGT1A4 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15430
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UGT1A6 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15431
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UGT1A7 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15432
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UGT1A8 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS15433
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UGT1A9 Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A9 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16797
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Ugt1a1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ugt1a1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS28491
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Ugt1a4 Rat Pre-designed siRNA Set A contains three designed siRNAs for Ugt1a4 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS16380
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UGT1A Human Pre-designed siRNA Set A contains three designed siRNAs for UGT1A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS27017
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Ugt1a Rat Pre-designed siRNA Set A contains three designed siRNAs for Ugt1a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-E72105
Human UGT1A1 is a uridine diphosphate glucuronosyltransferase (UGT). Human UGT1A1 participates in the glucuronidation pathway, which can convert small lipophilic molecules such as steroids, bilirubin, hormones and drugs into water-soluble, excretable metabolites .
Cat. No.: HY-E72106
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Human UGT1A3 is an UDP-glucuronosyltransferase. Human UGT1A3 catalyzes the glucuronidation of Estrone (HY-B0234), amine substrates, opioids, coumarins, flavonoids and anthraquinones. Human UGT1A3 binds to Chenodeoxycholic Acid (HY-76847) in the liver . Human UGT1A3 can be used in research related to cholestatic liver diseases .
Cat. No.: HY-E72107
Human UGT1A4 is a UDP-glucuronosyltransferase. Human UGT1A4 is the major enzyme catalyzing the glucuronidation of 25-hydroxyvitamin D3 (HY-32351) in the liver, and maintains vitamin D homeostasis by clearing 25-hydroxyvitamin D3. Human UGT1A4 regulates the substrate-dependent enzymatic activities of UGT1A1 and UGT1A6, while its own activity is also subject to substrate-dependent regulation by co-expressed UGT1A1 and UGT1A6 .
Cat. No.: HY-E72108
Human UGT1A6 is a UDP-glucuronosyltransferase. UGT1A6 catalyzes the glucuronidation of 5-hydroxytryptamine (HY-B1473A), 1-Naphthol (HY-Y1309), and Acetaminophen (HY-66005). Human UGT1A6 can be used in studies related to the pathogenesis of bladder cancer .
Cat. No.: HY-E72109
Human UGT1A7 is a UDP-glucuronosyltransferase. UGT1A7 catalyzes the glucuronidation of hydrophobic substrates, polycyclic aromatic hydrocarbons, dietary heterocyclic amines, and 1-Hydroxypyrene (HY-W014075). Human UGT1A7 is applicable to research related to sporadic colorectal cancer .
Cat. No.: HY-E72110
Human UGT1A8 is a UDP-glucuronosyltransferase. Human UGT1A8 catalyzes the transfer of glucuronosyl group from UDPGA to Dihydrotestosterone, forming DHT monoglucuronide. Human UGT1A8 catalyzes the transfer of glucuronosyl group from UDPGA to DHT monoglucuronide, introducing a second glucuronosyl group at the C2 ' position of the latter to form DHT diglucuronide. Human UGT1A8 catalyzes the glucuronidation reactions of coumarins, anthraquinones, flavonoids, phenolic compounds, catechol estrogens, primary amines including 4-Aminobiphenyl, and some opioids .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
